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Publ._peterkraiczy

Publications (2008-2009)
1. Kraiczy, P., Seling, A., Brissette, C. A., Rossmann, E., Hunfeld, K.-P., Bykowski, T., Burns,
L. H., Troese, M. J., Cooley, A.E., Miller, J. C., Brade, V., Wallich, R., Casjens, S., and B. Stevenson. Antibodies against Borrelia burgdorferi complement regulator-acquiring surface protein 2 (CspZ) as a serological marker of human Lyme disease. Clin. Vaccine Immunol., 2008, 15: 484-491. 2. Besier, S., J. Zander, B.C. Kahl, P. Kraiczy, V. Brade, T.A. Wichelhaus.The thymidine-
dependent small colony variant phenotype is associated with 2 hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. Antimicrob. Agents Chemother., 2008, 52: 2183-2189. 3. Bykowski, T., M. E. Woodman, A. E. Cooley, C. A. Brissette, R. Wallich, V. Brade, P.
Kraiczy, and B. Stevenson. Borrelia burgdorferi complement regulator-acquiring surface
proteins (BbCRASPs): Expression patterns during mammal-tick infection cycle. Int. J. Med.
Microbiol. 2008, 298 S1: 249-256.
4. Haupt, K., P. Kraiczy, R. Wallich, V. Brade, C. Skerka, and P. F. Zipfel. FHR-1, an
additional human plasma protein, binds to complement regulator-acquiring surface proteins of Borrelia burgdorferi. Int. J. Med. Microbiol., 2008, 298 S1: 287-291. 5. Hunfeld, K.P., Burg, S., Hanssen-Hübner, C., Karas, M., Brade, V., and P. Kraiczy. Changes
in the expression pattern of structural proteins after exposure of Borrelia burgdorferi to penicillin G and doxycycline. Int. J. Med. Microbiol., 2008, 298 S1: 325-332. 6. Siegel, C., P. Herzberger, C. Skerka, V. Brade, V. Fingerle, U. Schulte-Spechtel, B. Wilske, P. F. Zipfel, R. Wallich, and P. Kraiczy. Binding of complement regulatory protein factor H
enhance serum resistance of B. spielmanii sp. nov. Int. J. Med. Microbiol., 2008, 298 S1: 292-
294.
7. Kraiczy, P., J. Schreiber, C. Skerka, K. Haupt, V. Brade, R. Wallich, P.F. Zipfel. Assessment
of the regions within complement regulator-acquiring surface protein (CRASP)-2 of Borrelia burgdorferi required for interaction with host immune regulators FHL-1 and factor H. Int. J. Med. Microbiol., 2008, 298 S1:268-271. 8. Rossmann, E., P. Kraiczy, P. Herzberger, C. Skerka, M. Kirschfink, M. M. Simon, P. F.
Zipfel, and R. Wallich. BhCRASP-1 of relapsing fever spirochetes Borrelia hermsii is a factor H- and plasminogen-binding protein. Int. J. Med. Microbiol., 2008, 298 S1: 272-283. 9. Rossmann, E., V. Kitiratschky, H. Hoffman, M. M. Simon, P. Kraiczy, and R. Wallich.
BbCRASP-1 of the Lyme disease spirochetes induce antibodies to non-denatured structural determinants in humans. Int. J. Med. Microbiol., 2008, 298 S1: 284-286. 10. Sadik, C.D., Hunfeld, K.-P., Bachmann, M., Kraiczy, P., Eberhardt, W., Brade, V.,
Pfeilschifter, J., H. Mühl. Systematic analysis highlights the key role of TLR2/NF-B/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. Int. J. Biochem. Cell Biol. 2008, 40: 2508-2521. 11. Siegel, C., Schreiber, J., Haupt, K., Skerka, C., Brade, V., Simon, M.M., Stevenson, B., Wallich, R., Zipfel, P.F., and P. Kraiczy. Deciphering the ligand-binding sites in the Borrelia
burgdorferi
complement regulator-acquiring surface protein 2 (BbCRASP-2) required for
interactions with the human immune regulators factor H and factor H-like protein 1. J. Biol.
Chem., 2008, 283: 34855-34863.
12. Poggensee, G., Fingerle, V., Hunfeld, K.-P., Kraiczy, P., Krause, A., Matuschka, F.-R.,
Richter, D., Simon, M.M., Wallich, R., Hofman, H., Kohn, B., Lierz, M., Linde, A., Schneider, T., Strfaubinger, R., Stark, K., Süss, J., Talaska, T., und A. Jansen. Lyme-Borreliose: Forschungsbedarf und Forschungsansätze. Bundesgesundheitsblatt 2008, 50: 1329-1339. 13. Brissette, C.A., Haupt, K., Barthel, D., Cooley, A.E., Bowman, A., Skerka, C., Wallich, R., Zipfel, P.F., Kraiczy, P., and B. Stevenson. The Borrelia burgdorferi infection-associated
surface proteins ErpP, ErpA, and ErpC bind human plasminogen. Infect. Immun. 2009, 77:
300-306.
14. Herzberger, P., C. Siegel, C. Skerka, V. Fingerle, U. Schulte-Spechtel, B. Wilske, V. Brade, P. F. Zipfel, R. Wallich, and P. Kraiczy. Identification and characterization of the factor H and
FHL-1 binding complement regulator-acquiring surface protein 1 of the Lyme disease
spirochete Borrelia spielmanii sp. nov. Int. J. Med. Microbiol., 2009, 299: 141-154.
15. Morgenstern, K., Baljer, G., Norris, D.E., Kraiczy, P., Hanssen-Hübner, C., and K.-P.
Hunfeld. In vitro susceptibility of Borrelia spielmanii against antimicrobial agents commonly used for the treatment of Lyme disease. Antimicrob. Agents Chemother., 2009, 53: 1281-1284. 16. Grosskinsky S., Schott, M., Brenner, C., Cutler, S.J., Kraiczy, P., Zipfel, P.F., Simon, M.M.,
and R. Wallich. Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity. PLoS ONE. 2009, 4:e4858. 17. Kraiczy, P., Hanssen-Hübner, C., Kitiratschky, V., Brenner, C., Besier, S., Brade, V., Simon,
M. M., Skerka, C., Roversi, P., Lea, S. M., Stevenson, B., Wallich, R., and P. F. Zipfel. Mutational analyses of the BbCRASP-1 protein of Borrelia burgdorferi identifies residues relevant for the architecture and binding of the host complement regulators FHL-1 and factor H. Int. J. Med. Microbiol., 2009, 299: 255-268. 18. Hunfeld, K.-P., and P. Kraiczy. When is the best time to order a Western blot and how should
it be interpreted? Curr. Probl. Dermatol., 2009, 37: 167-177. 19. Kenedy, M. R., Vuppala, S. R., Siegel, C., Kraiczy, P., and D. R. Akins. CspA-mediated
binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi. Infect. Immun., 2009, 77: 2773-2782.

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(gastbeitrag: 'phytos' haben f\374r senioren viele vorteile)

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George H Elder, Richard J Hift, Peter N MeissnerPublic attention has been drawn to the acute porphyriasin the past few years by speculation that they affected thecharacter of George III and the creative genius of VincentAcute intermittent porphyriaAutosomal dominant; acute attacks only; no cutaneousvan Gogh. During the same period, there have beenmanifestations. Three families with homozygous

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