Publ._peterkraiczy

Publications (2008-2009)
1. Kraiczy, P., Seling, A., Brissette, C. A., Rossmann, E., Hunfeld, K.-P., Bykowski, T., Burns,
L. H., Troese, M. J., Cooley, A.E., Miller, J. C., Brade, V., Wallich, R., Casjens, S., and B. Stevenson. Antibodies against Borrelia burgdorferi complement regulator-acquiring surface protein 2 (CspZ) as a serological marker of human Lyme disease. Clin. Vaccine Immunol., 2008, 15: 484-491. 2. Besier, S., J. Zander, B.C. Kahl, P. Kraiczy, V. Brade, T.A. Wichelhaus.The thymidine-
dependent small colony variant phenotype is associated with 2 hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. Antimicrob. Agents Chemother., 2008, 52: 2183-2189. 3. Bykowski, T., M. E. Woodman, A. E. Cooley, C. A. Brissette, R. Wallich, V. Brade, P.
Kraiczy, and B. Stevenson. Borrelia burgdorferi complement regulator-acquiring surface
proteins (BbCRASPs): Expression patterns during mammal-tick infection cycle. Int. J. Med.
Microbiol. 2008, 298 S1: 249-256.
4. Haupt, K., P. Kraiczy, R. Wallich, V. Brade, C. Skerka, and P. F. Zipfel. FHR-1, an
additional human plasma protein, binds to complement regulator-acquiring surface proteins of Borrelia burgdorferi. Int. J. Med. Microbiol., 2008, 298 S1: 287-291. 5. Hunfeld, K.P., Burg, S., Hanssen-Hübner, C., Karas, M., Brade, V., and P. Kraiczy. Changes
in the expression pattern of structural proteins after exposure of Borrelia burgdorferi to penicillin G and doxycycline. Int. J. Med. Microbiol., 2008, 298 S1: 325-332. 6. Siegel, C., P. Herzberger, C. Skerka, V. Brade, V. Fingerle, U. Schulte-Spechtel, B. Wilske, P. F. Zipfel, R. Wallich, and P. Kraiczy. Binding of complement regulatory protein factor H
enhance serum resistance of B. spielmanii sp. nov. Int. J. Med. Microbiol., 2008, 298 S1: 292-
294.
7. Kraiczy, P., J. Schreiber, C. Skerka, K. Haupt, V. Brade, R. Wallich, P.F. Zipfel. Assessment
of the regions within complement regulator-acquiring surface protein (CRASP)-2 of Borrelia burgdorferi required for interaction with host immune regulators FHL-1 and factor H. Int. J. Med. Microbiol., 2008, 298 S1:268-271. 8. Rossmann, E., P. Kraiczy, P. Herzberger, C. Skerka, M. Kirschfink, M. M. Simon, P. F.
Zipfel, and R. Wallich. BhCRASP-1 of relapsing fever spirochetes Borrelia hermsii is a factor H- and plasminogen-binding protein. Int. J. Med. Microbiol., 2008, 298 S1: 272-283. 9. Rossmann, E., V. Kitiratschky, H. Hoffman, M. M. Simon, P. Kraiczy, and R. Wallich.
BbCRASP-1 of the Lyme disease spirochetes induce antibodies to non-denatured structural determinants in humans. Int. J. Med. Microbiol., 2008, 298 S1: 284-286. 10. Sadik, C.D., Hunfeld, K.-P., Bachmann, M., Kraiczy, P., Eberhardt, W., Brade, V.,
Pfeilschifter, J., H. Mühl. Systematic analysis highlights the key role of TLR2/NF-B/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. Int. J. Biochem. Cell Biol. 2008, 40: 2508-2521. 11. Siegel, C., Schreiber, J., Haupt, K., Skerka, C., Brade, V., Simon, M.M., Stevenson, B., Wallich, R., Zipfel, P.F., and P. Kraiczy. Deciphering the ligand-binding sites in the Borrelia
burgdorferi complement regulator-acquiring surface protein 2 (BbCRASP-2) required for
interactions with the human immune regulators factor H and factor H-like protein 1. J. Biol.
Chem., 2008, 283: 34855-34863.
12. Poggensee, G., Fingerle, V., Hunfeld, K.-P., Kraiczy, P., Krause, A., Matuschka, F.-R.,
Richter, D., Simon, M.M., Wallich, R., Hofman, H., Kohn, B., Lierz, M., Linde, A., Schneider, T., Strfaubinger, R., Stark, K., Süss, J., Talaska, T., und A. Jansen. Lyme-Borreliose: Forschungsbedarf und Forschungsansätze. Bundesgesundheitsblatt 2008, 50: 1329-1339. 13. Brissette, C.A., Haupt, K., Barthel, D., Cooley, A.E., Bowman, A., Skerka, C., Wallich, R., Zipfel, P.F., Kraiczy, P., and B. Stevenson. The Borrelia burgdorferi infection-associated
surface proteins ErpP, ErpA, and ErpC bind human plasminogen. Infect. Immun. 2009, 77:
300-306.
14. Herzberger, P., C. Siegel, C. Skerka, V. Fingerle, U. Schulte-Spechtel, B. Wilske, V. Brade, P. F. Zipfel, R. Wallich, and P. Kraiczy. Identification and characterization of the factor H and
FHL-1 binding complement regulator-acquiring surface protein 1 of the Lyme disease
spirochete Borrelia spielmanii sp. nov. Int. J. Med. Microbiol., 2009, 299: 141-154.
15. Morgenstern, K., Baljer, G., Norris, D.E., Kraiczy, P., Hanssen-Hübner, C., and K.-P.
Hunfeld. In vitro susceptibility of Borrelia spielmanii against antimicrobial agents commonly used for the treatment of Lyme disease. Antimicrob. Agents Chemother., 2009, 53: 1281-1284. 16. Grosskinsky S., Schott, M., Brenner, C., Cutler, S.J., Kraiczy, P., Zipfel, P.F., Simon, M.M.,
and R. Wallich. Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity. PLoS ONE. 2009, 4:e4858. 17. Kraiczy, P., Hanssen-Hübner, C., Kitiratschky, V., Brenner, C., Besier, S., Brade, V., Simon,
M. M., Skerka, C., Roversi, P., Lea, S. M., Stevenson, B., Wallich, R., and P. F. Zipfel. Mutational analyses of the BbCRASP-1 protein of Borrelia burgdorferi identifies residues relevant for the architecture and binding of the host complement regulators FHL-1 and factor H. Int. J. Med. Microbiol., 2009, 299: 255-268. 18. Hunfeld, K.-P., and P. Kraiczy. When is the best time to order a Western blot and how should
it be interpreted? Curr. Probl. Dermatol., 2009, 37: 167-177. 19. Kenedy, M. R., Vuppala, S. R., Siegel, C., Kraiczy, P., and D. R. Akins. CspA-mediated
binding of human factor H inhibits complement deposition and confers serum resistance in Borrelia burgdorferi. Infect. Immun., 2009, 77: 2773-2782.

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