Publication_list_kumagai_separated_en

Original Papers
1.
“Direct Catalytic Asymmetric Intramolecular Conjugate Addition of Thioamide to α,β-Unsaturated Ester”
Yuta Suzuki, Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
Chem. Eur. J. 2011, in press.
“Asymmetric Synthesis of Isothiazoles Through Cu Catalysis: Direct Catalytic Asymmetric Conjugate Addition of
Allyl Cyanide to α,β-Unsaturated Thioamides”
Yuka Yanagida, Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
Angew. Chem., Int. Ed. 2011, 50(34), 7910-7914.
“La/Ag Heterobimetallic Catalysis: Catalytic Asymmetric Conia-ene Reaction”
Akinobu Matsuzawa, Tomoyuki Mashiko, Naoya Kumagai,* Masakatsu Shibasaki*
Angew. Chem., Int. Ed. 2011, 50(33), 7616-7619.
“A Simplified Catalytic System for Direct Catalytic Asymmetric Aldol Reaction of Thioamides; Application to an
Enantioselective Synthesis of Atorvastatin”
Yuji Kawato, Mitsutaka Iwata, Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
Tetrahedron 2011, 67(35), 6539-6546.
“Direct Catalytic Enantio- and Diastereoselective Aldol Reaction of Thioamides”
Mitsutaka Iwata, Ryo Yazaki, I-Hon Chen, Devarajulu Sureshkumar, Naoya Kumagai,* Masakatsu Shibasaki*
J. Am. Chem. Soc. 2011, 133(14), 5554-5560.
“Cooperative Activation of Alkyne and Thioamide Functionalities; Direct Catalytic Asymmetric Conjugate Addition
of Terminal Alkynes to α,β-Unsaturated Thioamides”
Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
Chem. Asian J. 2011, 6(7), 1778-1790.
“Enantioselective Synthesis of a GPR40 Agonist AMG 837 via Catalytic Asymmetric Conjugate Addition of Terminal
Alkyne to α,β-Unsaturated Thioamide”
Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
Org. Lett. 2011, 13(5), 952-955.
“Catalytic Asymmetric Hydroxylation of α-Alkoxycarbonyl Amides with a Pr(OiPr)3/Amide-Based Ligand Catalyst”
Sho Takechi, Naoya Kumagai,* and Masakatsu Shibasaki*
Tetrahedron Lett. 2011, 52(17), 2140-2143.
“Catalytic Asymmetric Amination of N-Nonsubstituted α-Alkoxycarbonyl Amides: Concise Enantioselective Total
Synthesis of Mycestericin F and G”
Farouk Berhal, Sho Takechi, Naoya Kumagai,* and Masakatsu Shibasaki*
Chem. Eur. J. 2011, 17(6), 1915-1921.
10. “Expanding Stereochemical and Skeletal Diversity Derived from Petasis Reactions Using 1,3 Dipolar Cycloadditions” Giovanni Muncipinto, Taner Kaya, J. Anthony Wilson, Naoya Kumagai, Paul A. Clemons, and Stuart L. Schreiber*
Org. Lett. 2010, 12(22), 5230-5233.
11. “Direct Catalytic Asymmetric Conjugate Addition of Terminal Alkynes to α,β-Unsaturated Thioamides” Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2010, 132(30), 10275-10277.
12. “Direct Catalytic Asymmetric Aldol Reaction of Thioamides: A Concise Asymmetric Synthesis of (R)-Fluoxetine” Mitsutaka Iwata, Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
Tetrahedron: Asymmetry 2010, 21(13-14), 1688-1694.
13. “Solvent-Dependent Self-Discrimination of Bis(2-hydroxyphenyl)diamides” Akinobu Matsuzawa, Akihiro Nojiri, Naoya Kumagai,* and Masakatsu Shibasaki*
Chem. Eur. J. 2010, 16(17), 5036-5042.
14. “Direct Catalytic Asymmetric Addition of Allyl Cyanide to Ketones via Soft-Lewis Acid/Hard Brønsted Base/Hard Lewis Base Cooperative Catalysis”
Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2010, 132(15), 5522-5531.
15. “Catalytic Asymmetric Conjugate Addition of α-Cyanoketones For the Construction of a Quaternary Stereogenic Center”
Yuji Kawato, Noriko Takahashi, Naoya Kumagai,* and Masakatsu Shibasaki*
Org. Lett. 2010, 12(7), 1484-1487.
16. “Catalytic Asymmetric Nitro-Mannich Reactions with a Yb/K Heterobimetallic Catalyst” Tatsuya Nitabaru, Naoya Kumagai,* and Masakatsu Shibasaki*
Molecules 2010, 15(3), 1280-1290.
17. “Direct Catalytic Asymmetric Aldol Reactions of Thioamides: Toward a Stereocontrolled Synthesis of 1,3-Polyols” Mitsutaka Iwata, Ryo Yazaki, Yuta Suzuki, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2009, 131(51), 18244-18245.
18. “Managing Highly Coordinative Substrates in Asymmetric Catalysis: a Catalytic Asymmetric Amination with a Lanthanum-based Ternary Catalyst”
Tomoyuki Mashiko, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2009, 131(41), 14990-14999.
19. “anti-Selective Catalytic Asymmetric Nitroaldol Reaction via a Heterobimetallic Heterogeneous Catalyst” Tatsuya Nitabaru, Akihiro Nojiri, Makoto Kobayashi, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2009, 131(38), 13860-13869.
20. “Direct Catalytic Asymmetric Mannich-type Reaction of Thioamides” Yuta Suzuki, Ryo Yazaki, Naoya Kumagai,* and Msakatsu Shibasaki*
Angew. Chem., Int. Ed. 2009, 48(27), 5026-5029.
21. “Linking Structural Dynamics and Functional Diversity in Asymmetric Catalysis” Akihiro Nojiri, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2009, 131(10), 3779-3784.
22. “Direct Catalytic Asymmetric Addition of Allyl Cyanide to Ketones” Ryo Yazaki, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2009, 131(9), 3195-3197.
23. “Direct Catalytic Asymmetric Addition of Allylic Cyanides to Ketoimines” Ryo Yazaki, Tatsuya Nitabaru, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2008, 130(44), 14477-14479.
24. “An Improved Lanthanum Catalytic System for Asymmetric Amination; Toward a Practical Asymmetric Synthesis of AS-3201 (Ranirestat)”
Tomoyuki Mashiko, Naoya Kumagai,* and Masakatsu Shibasaki*
Org. Lett. 2008, 10(13), 2725-2728.
25. “Asymmetric Catalysis via Dynamic Substrate/Ligand Rare Earth Metal Conglomerate” Akihiro Nojiri, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2008, 130(17), 5630-5631.
26. “A Catalytic Asymmetric anti-Selective Nitroaldol Reaction with a Neodymium Sodium Heterobimetallic Complex” Tatsuya Nitabaru, Naoya Kumagai,* and Masakatsu Shibasaki*
Tetrahedron Lett. 2008, 49(2), 272-276.
27. “En Route to an Efficient Asymmetric Synthesis of AS-3201” Tomoyuki Mashiko, Keiichi Hara, Daisuke Tanaka, Yuji Fujiwara, Naoya Kumagai,* and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2007, 129(37), 11342-11343.
28. “Catalytic Nucleophilic Activation of Acetonitrile via a Cooperative Catalysis of Cationic Ru Complex, DBU, and NaPF6”
Naoya Kumagai,* Shigeki Matsunaga, and Masakatsu Shibasaki*
Tetrahedron 2007, 63(35), 8598-8608.
29. “Short Synthesis of Skeletally and Stereochemically Diverse Small Molecules by Coupling Petasis Condensation Reactions to Cyclization Reactions” Naoya Kumagai, Giovanni Muncipinto, and Stuart L. Schreiber* Angew. Chem., Int. Ed. 2006, 45(22), 3635-3638.
30. “Catalytic Chemoselective Addition of Acetonitrile to Enolizable Aldehydes with Cationic Ru Complex/DBU Combination”
Naoya Kumagai, Shigeki Matsunaga, and Masakatsu Shibasaki*
Chem. Commun. 2005, (28) 3600-3602.
31. “Non-C2-symmetric, Chirally Economical, and Readily Tunable Linked-BINOLs: Design and Application in Direct Asymmetric Mannich-type Reaction”
Takamasa Yoshida, Hiroyuki Morimoto, Naoya Kumagai, Shigeki Matsunaga, and Masakatsu Shibasaki*
Angew. Chem. Int. Ed. 2005, 44(22), 3470-3474.
32. “An Efficient Synthesis of Bicyclic Amidines by Intramolecular Cyclization” Naoya Kumagai, Shigeki Matsunaga, and Masakatsu Shibasaki*
Angew. Chem., Int. Ed. 2004, 43(4), 478-482.
33. “Direct catalytic Asymmetric Mannich-type Reaction of Hydroxyketone Using a Et2Zn/linked-BINOL Complex: Synthesis of Either anti-α or syn-β-Amino Alcohols”
Shigeki Matsunaga, Takamasa Yoshida, Hiroyuki Morimoto, Naoya Kumagai, and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2004, 126(28), 8277-8785.
34. “Cooperative Catalysis of a Cationic Ruthenium Complex, Amine Base, and Na Salt: Catalytic Activation of Acetonitrile as Nucleophile”
Naoya Kumagai, Shigeki Matsunaga, and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2004, 126(42), 13632-13633.
35. “Direct Catalytic Aldol-Type Reactions Using RCH2CN” Yutaka Suto, Naoya Kumagai, Shigeki Matsunaga, Motomu Kanai, and Maskatsu Shibasaki*
Org. Lett. 2003, 5(17), 3147-3150.
36. “anti-Selective Direct Catalytic Asymmetric Mannich-type Reaction of Hydroxyketone Providing β-Amino Alcohols” Shigeki Matsunaga, Naoya Kumagai, Shinji Harada, and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2003, 125(16), 4712-4713.
37. “Direct Catalytic Asymmetric Michael Reaction of Hydroxyketones: Asymmetric Zn Catalysis with a Et2Zn/Linked-BINOL Complex”
Shinji Harada, Naoya Kumagai, Tomofumi Kinoshita, Shigeki Matsunaga, and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2003, 125(9), 2582-2590.
38. “Direct Catalytic Asymmetric Aldol Reaction of Hydroxyketones: Asymmetric Zn Catalysis with a Et2Zn/Linked-BINOL Complex”
Naoya Kumagai, Shigeki Matsunaga, Tomofumi Kinoshita, Shinji Harada, Shigemitsu Okada, Shigeru Sakamoto,
Kentaro Yamaguchi, and Masakatsu Shibasaki*
J. Am. Chem. Soc. 2003, 125(8), 2169-2178.
39. “Reaction Design in View of Practicality” Masakatsu Shibasaki, and Naoya Kumagai
Kagaku (Kyoto, Japan) 2002, 57(12), 27-29.
40. “Enantioselective 1,4-Addition of Unmodified Ketone Catalyzed by a Bimetallic Zn-Zn-linked-BINOL Complex” Naoya Kumagai, Shigeki Matsunaga and Masakatsu Shibasaki*
Org. Lett. 2001, 3(26), 4251-4254.
41. “Direct Catalytic Enantio- and Diastereoselective Aldol Reaction Using a Zn-Zn-Linked-BINOL Complex: A Practical Synthesis of syn-1,2-Diols”
Naoya Kumagai, Shigeki Matsunaga, Naoki Yoshikawa, Takashi Ohshima, and Masakatsu Shibasaki*
Org. Lett. 2001, 3(10), 1539-1542.
42. “Direct Catalytic Asymmetric Aldol Reaction: Synthesis of Either syn- or anti-α,β-dihydroxyketones” Naoki Yoshikawa, Naoya Kumagai, Shigeki Matsunaga, Guido Moll, Takashi Ohshima, Takeyuki Shzuki, and
Masakatsu Shibasaki*
J. Am. Chem. Soc. 2001, 123(10), 2466-2467.
43. “An Efficient Method for the Synthesis of Versatile Intermediate Leading to 13-Deoxy- and 9,13-Dideoxyphorbors” Akihiro Sekine, Naoya Kumagai, Koichiro Uotsu, Takashi Ohshima, and Masakatsu Shibasaki*
Tetrahedron Lett. 2000, 41(4), 509-513.

Reviews and Accounts
1.
“Recent Advances in Direct Catalytic Asymmetric Transformations Under Proton Transfer Conditions”
Naoya Kumagai,* and Masakatsu Shibasaki*
Angew. Chem., Int. Ed. 2011, 50(21), 4760-4772.
“Development of Atom-Economical Catalytic Asymmetric Reactions Under Proton Transfer Conditions: Construction
of Tetrasubstituted Stereogenic Centers and Their Application to Therapeutics”
Naoya Kumagai*
Chem. Pharm. Bull. 2011, 59(1), 1-22.
“Inventing and Understanding Catalytic, Enantioselective Reactions”
Masakatsu Shibasaki,* Naoya Kumagai, and Tomoyuki Mashiko
Curr. Opin. Drug Discov. Dev. 2009, 12(6), 862-875.
“Recent Progress in Asymmetric Bifunctional Catalysis Using Multimetallic Systems”
Masakatsu Shibasaki,* Motomu Kanai, Shigeki Matsunaga, and Naoya Kumagai
Acc. Chem. Res. 2009, 42(8), 1117-1127.
“Strategies for Constructing Diverse Chiral Environments in Multimetallic Bifunctional Asymmetric Catalysis”
Masakatsu Shibasaki,* Shigeki Matsunaga, and Naoya Kumagai
Synlett 2008, (11), 1583-1602.

Book Chapter
1.
In Topics in Organometallic Chemistry,
“Multimetallic Multifunctional Catalysts For Asymmetric Reactions”, Springer (2011).
Masakatsu Shibasaki, Motomu Kanai, Shigeki Matsunaga, and Naoya Kumagai
(2S,2S_,5S,5S_)1 1,1-(1,2-Ethanediyl)-bis[2,5-diphenyl-(2R,2R_,5R,5R_)” in e-EROS: Encyclopedia of Reagents for Organic Synthesis
(2010).
Naoya Kumagai
In Topics in Organometallic Chemistry, Eds. Ikariya T. and Shibasaki M.,
“Chemistry of Bifunctional Molecular Catalysis” Springer, Weinheim (2010).
Masakatsu Shibasaki, Motomu Kanai, Shigeki Matsunaga, and Naoya Kumagai
“1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)benzene1 and 1,2-Bis ((2S,5S)-2,5-diisopropylphospholan-1-yl)
benzene” in e-EROS: Encyclopedia of Reagents for Organic Synthesis (2009).
Naoya Kumagai
In Acid Catalysis in Modern Organic Synthesis, Eds. Yamamoto H. and Ishihara, K., “Lanthanide Lewis Acid”
Wiley-VCH Weinheim (2008).
Masakatsu Shibasaki, Shigeki Matsunaga, and Naoya Kumagai
In Multimetallic Catalysis in Organic Synthesis, Eds. Yoshinori Yamamoto and Masakatsu Shibasaki, Wiley-VCH
(2005)
Masakatsu Shibasaki, Shigeki Matsunaga, and Naoya Kumagai
In Catalysis For Fine Chemical Synthesis, Ed. Stan Roberts, Wiley-VCH (2004)
Masakatsu Shibasaki. Shigeki Matsunaga, and Naoya Kumagai
In Modern Aldol Reactions, Ed. Reiner Mahrwald, Wiley-VCH (2003)
Masakatsu Shibasaki, Shigeki Matsunaga, and Naoya Kumagai

Patents
1.
Tatsuya Nitabaru, Naoya Kumagai, Masakatsu Shibasaki Asymmetric Catalyst for anti-Selective Nitroaldol Reaction PCT/JP2010/000387 Tatsuya Nitabaru, Naoya Kumagai, Masakatsu Shibasaki Asymmetric Catalyst for anti-Selective Nitroaldol Reaction JP2009-165211. Tomoyuki Mashiko, Naoya Kumagai, Masakatsu Shibasaki Asymmetric Catalyst forAmination JP2008-031321. Tatsuya Nitabaru, Naoya Kumagai, Masakatsu Shibasaki Asymmetric Catalyst for anti-Selective Nitroaldol Reaction JP2007-285122. Tomoyuki Mashiko, Naoya Kumagai, Masakatsu Shibasaki Asymmetric Catalyst for Amination JP2008-031321.
Lectures
1.
EPS High-Technology Forum Montreal, Canada Title: Organic Synthesis for a Sustainable World Aug 16, 2011 The Scripps Research Institute, CA, USA Title: Soft Lewis Acid/Hard Brønsted Base Cooperative Catalysis Aug 5, 2011 Boston College, MA, USA Title: Soft Lewis Acid/Hard Brønsted Base Cooperative Catalysis Aug 2, 2011 MIT, MA, USA Title: Soft Lewis Acid/Hard Brønsted Base Cooperative Catalysis Aug 1, 2011 University of Colorado, CO, USA Title: Soft Lewis Acid/Hard Brønsted Base Cooperative Catalysis for the Construction of Tetrasubstituted Stereogenic Centers Aug 9, 2010 Tampere University of Technology, Tampere University of Technology, Finland Title: Recent Progress in Asymmetric C–C Bond formation via Proton Transfer July 19, 2010 RSC-CSJ Joint Symposium—Chemistry for a Sustainable World RSC Burlington House, London, GB Title: Atom-economical Catalytic Asymmetric Reactions and Their Application to Efficient Synthesis of Therapeutics July 16, 2010 BIT’s 1st Annual World Congress in Catalytic Asymmetric Synthesis Beijing Convention Center, Beijing, China Title: Rare Earth Metal/Amide-Based Ligand Complexes: Structural Dynamics, Functional Diversity, and Asymmetric Catalysis May 21, 2010 Award Address at the Annual Meeting of Pharmaceutical Society of Japan “Development of Atom-economical Catalytic Asymmetric Reactions and Their Application to Practical Synthesis of Therapeutics” Okayama Convention Center, Okayama, Japan Mar 28, 2010 “Asymmetric Catalysis with Rare Earth Metal/Amide Ligand Complexes” Tampere University of Technology, Tampere, Finland Jun 27, 2008 “Direct Catalytic Asymmetric Reactions Using a Zn/Linked-BINOL Complexes” Lecture Hall, Chiba University, Chiba, Japan Dec 6, 2003

Source: http://www.bikaken.or.jp/research/group/shibasaki/shibasaki-lab/lab-info/individual/dat/nkumagai_paper2.pdf