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Microsoft word - 005-guideline_bullouspemphigoid_2011.doc

target antigens dermo-epidermal junction F (Level of evidence 1, Strength of recommendations A) F 2.3.1 Azathioprine (Level of evidence 2, Strength of recommendations B) 2.3.2 Methotrexate (Level of evidence 3, Strength of recommendations C) 2.3.3 Cyclophosphamide (Level of evidence 4, Strength of recommendations C) 2.3.4 Mycophenolate mofetil (Level of evidence 2, Strength of recommendations B) 2.3.5 Cyclosporine (Level of evidence 4, Strength of recommendations C) 2.3.6 Chlorambucil (Level of evidence 3, Strength of recommendations C) F (Level of evidence 4, Strength of recommendations C) 2.4.1 Dapsone (Level of evidence 3, Strength of recommendations C) 2.4.2 Sulfonamides (Level of evidence 3, Strength of recommendations C) sulfapyridine Glucose-6 phosphate dehydrogenase (G6PD) deficiency 3.1 Intravenous immunoglobulin (IVIG) (Level of evidence 3, Strength of recommendations 3.2 Plasmapheresis (Plasma exchange) (Level of evidence 2, Strength of recommendations B) 1. Kulthanan K, Chularojanamontri L, Tuchinda P, Sirikudta W, Pinkaew S. Prevalence and Clinical features of Thai patients with bul ous pemphigoid. Asian Pac J Al ergy Immunol 2011; 29: 66-72. 2. Mutasim DF. Management of autoimmune bul ous diseases: pharmacology and therapeutics. J Am 3. Wojnarowska F, Kirtschig G, Highet AS, Venning VA, Khumalo NP. Guidelines for the management of bul ous pemphigoid. Br J Dermatol 2002 147: 214-21. 4. Kirtschig G, Middleton P, Bennet C, Mur el DF, Wojnarowska F, Khumalo NP. Interventions for bul ous pemphigoid. Cochrane Database Syst Rev 2010 Oct6; (10): CD 002292. 5. Heilborn JD, Stahle-Backdahl M, Albertioni F, Vassilaki I, Peterson C, Stephansson E. Low- dose oral pulse methotrexate as monotherapy in elderly patients with bul ous pemphigoid. J Am Acad Dermatol 1999; 40:741-9. 6. Itoh T, Hosokawa H, Shirai Y, Horio T. Successful treatment of bul ous pemphigoid with pulsed intravenous cyclophosphamide. Br J Dermatol 1996; 134: 931-3. 7. Venning VA, Mil ard PR, Wojnarowska F. Dapsone as first line therapy for bul ous pemphigoid. Br 8. Bouscarat F, Chosidow O, Picard-Dahan C, et al. Treatment of bul ous pemphigoid with dapsone: retrospective study of thirty-six cases. J Am Acad Dermatol 1996; 34: 683-4. 9. Joly P, Roujeau JC, Benichou J, Picard C, Dreno B, Delaporte E, et al. A comparison of oral and topical corticosteroids in patients with bul ous pemphigoid. N Engl J Med 2002; 346: 321-7. 10. Fiverson P, Breneman L, Rosen B, Hersh S, Cardone S, Mutasim D. Nicotinamide and tetracycline therapy of bul ous pemphigoid. Arch Dermatol 1994; 130: 753-8. 11. Morel P, Guil aume JC. Treatment of bul ous pemphigoid with prednisolone only: 0.75 mg/kg/day versus 1.25 mg/kg/day. A multicenter randomized study. Ann Dermatol Venereol 1984; 111: 925-8. 12. Dreno B, Sassolas B, Lacour P, Montpoint S, Lota I, Giordano F, et al. Methylprednisolone versus prednisolone methylsulfobenzoate in pemphigoid: a comparative multicenter study. Ann Dermatol Venereol 1993; 120: 518-21. 13. Piamphongsan T. Dapsone for the treatment of bul ous pemphigoid. Asain Pac J Al ergy Immunol 14. Burton JL, Harman RR, Peachey RD, Warin RP. Azathioprine plus prednisone in treatment of 15. Guil aume JC, Vail ant L, Bernard P, Picard C, Prost C, Labeil e B, et al. Control ed trial of azathioprine and plasma exchange in addition to prednisolone in the treatment of bul ous pemphigoid. Arch Dermatol 1993; 129: 49-53. 16. Roujeau JC, Guil aume JC, Morel P, et al. Plasma exchange in bul ous pemphigoid Lancet. 1984; 2: 17. Hofmann S, Thoma-Uszynski S, Hunziker T, et al. Severity and phenotype of bul ous pemphigoid relate to antibody profile against the NH2- and COOH-terminal regions of the BP180 ectodomain. J 18. Tsuji-Abe Y, Akiyama M, Yamanaka Y, Kikuchi T, Sato-Matsumura KC, Shimizu H. Cor elation of clinical severity and ELISA indices for the NC16A domain of BP180 measured using BP180 ELISA kit in bul ous pemphigoid. J Dermatol Sci 2005; 37: 145-9. 19. Schmidt E, Obe K, Brocker EB, Zil ikens D. Serum levels of autoantibodies to BP180 cor elate with disease activity in patients with bul ous pemphigoid. Arch Dermatol 2000; 136: 174-8. Level of evidence Strength of recommendation

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Paed2002-progbk.cdr

The Overactive Bladder C. DEFOURNEY, E. VAN LAECKE, A. RAES, J. DEHOORNE, G. MOSIELLO, M.L. CAPITANUCCI, P. MASTRACCI, M. MOSCONI, Paediatric Uro- Nephrologic Centre (PUNC), Ghent University Pediatric Surgery, Urodynamic Unit, Bambino Gesù Children's LONG TERM OUTCOME OF TREATMENT OF NON NEUROPATHIC IS STOLLER AFFERENT NERVE STIMULATION (SANS) USEFUL AND BLADDER SPHINCTER DYSFUNCTION (NN

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Die Tamiflu-Lüge Milliarden haben Regierungen ausgegeben für das Grippemedikament Tamiflu, um gegen eine Pandemie gewappnet zu sein. Nun warnen Wissenschaftler: Die veröffentlichten Daten zu dem Mittel sind massiv geschönt. Etwa für jeden fünften Bundesbürger liegen sie bereit: Grippemittel, die im Falle einer Pandemie die lebensgefährlichen Komplikationen der Infektion entschärfen

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