English books 1. Kaku K, Matsuda M, Kaneko T, Permutt MA: Genetic analysis of diabetic susceptibility in inbred mouse
strains. In Tai Hee Lee (Ed) Recent advances in insulin therapy pp.127㹼 130, Springer International (Heidelberg, Germany), 1990.
2. Matsuda M, DeFronzo RA : In vivo Measurement of Insulin Sensitivity in Human Clinical Research in
Diabetes and Obesity In Draznin B, Rizza R (Ed) Part I: Methods, Assessment, and Metabolic Regulation pp.23㹼 65, Humana Press (Totowa, NJ, USA㸧 , 1997.
Kaku K, Tsuchiya M, Matsuda M, Inoue Y, Kaneko T, Yanaihara N: Light and agonist alter vasoactive
intestinal peptide binding and intracellular accumulation of adenosine 3',5'-monophosphate in the rat pineal gland. Endocrinology 117:2371-2375, 1985.
Hatao K, Kaku K, Matsuda M, Tsuchiya M, Kaneko,T: Sulfonylurea stimulates liver fructose 2,6-
bisphosphate formation in proportion to its hypoglycemic action. Diabetes Res Clin Pract 1:49-53, 1985.
Kaku K, Matsuda M, Matsutani A, Kaneko T: Effect of tolbutamide on fructose-6-phosphate, 2-kinase
and fructose-2,6-bisphoshatase in rat liver. Biochem Biophys Res Commun 139:687-692, 1986.
Matsuda M, Kaku K, Hatao K, Kaneko T: Tolbutamide and insulin stimulation of
fructose-2,6-bisphosphate formation in hepatocytes differ. Diabetes Res Clin Pract. 2:347-353, 1986.
Matsuda M, Kaku K, Kaneko T: Regulation of muscle fructose 2,6-bisphosphate levels by sulfonylureas. Endocrinol Jpn 33:913-917, 1986.
Tsuchiya M, Kaku K, Matsuda M, Kaneko T, Yanaihara N: Demonstration of receptors specific for
peptide N-terminal histidine and C-terminal isoleucine (PHI) using rat PHI and rat dispersed pineal cells. Biomedical Research 8:45-51, 1987.
Fujii S, Matsuda M, Okuya S, Yoshizaki Y, Miura-Kora Y, Kaneko T: Fructose-6-phosphate,2-kinase
activity in human erythrocytes. Blood 70:1211-1213, 1987.
Kora-Miura Y, Fujii S, Matsuda M, Sato Y, Kaku K, Kaneko T: Electrophoretic determination of
fructose 6-phosphate,2-kinase. Anal Biochem 170:372-375, 1988.
Tanaka H, Shinohara K, Tanaka M, Matsuda M, Kaneko T: Flow cytometry analysis and gamma
interferon production of peripheral blood mononuclear cells in aplastic anemia. Jpn Arch Int Med
10. Shinohara K, Tanaka M, Matsuda M, Tanaka H, Fujii Y, Yamada K, Kaneko T: Gamma interferon
production and two-color fluorescence flow cytometry analysis of peripheral blood mononuclear cells in
allogeneic bone marrow transplant recipients. Acta Haematol Jpn 53:76-83, 1990.
11. Matsuda M, Kaku K, Aoki M, Inoue H, Kaneko T: Sulfonylurea enhances insulin-induced acetyl
coenzyme A carboxylase activity in rat adipocytes. Horm Metab Res 23:209-212, 1991.
12. Matsutani A, Kaku K, Aoki M, Mori K, Matsuda M, Kaneko T: Possible mechanism of proteolysis for
the extrapancreatic action of tolbutamide. Diabetes Res Clin Pract 12:35-40, 1991.
13. Shinohara K, Ayame H, Tanaka M, Matsuda M, Ando S, Tajiri M: Increased production of tumor
necrosis factor-alpha by peripheral blood mononuclear cells in the patients with aplastic anemia. Am J Hematol 37:75-79, 1991.
14. Fujii S, Kaku K, Andou S, Nakayama H, Suetsugu N, Inoue M, Yoshizaki Y, Matsuda M, Tanaka M,
Okafuji S, et al.: Glucose and lipid metabolism during long-term antihypertensive treatment with indapamide in non-insulin-dependent diabetic patients. Clin Ther. 15:1041-50., 1993.
15. Bonora E, Bonadonna RC, Del Prato S, Gulli G, Solini A, Matsuda M, DeFronzo RA: In vivo glucose
metabolism in obese and type II diabetic subjects with or without hypertension. Diabetes 42:764-772, 1993.
16. Del Prato S, Leonetti F, Simonson DC, Sheehan P, Matsuda M, DeFronzo RA: Effect of sustained
physiologic hyperinsulinemia and hyperglycemia on insulin secretion and insulin sensitivity in man.
17. Matsuda M: In vivo techniques for clinical studies of glucose metabolism. Bulletin of the Yamaguchi
18. Giordano M, Matsuda M, Sanders L, Canessa ML, DeFronzo RA: Effects of angiotensin-converting
enzyme inhibitors, Ca2+ channel antagonists, and alpha-adrenergic blockers on glucose and lipid
metabolism in NIDDM patients with hypertension. Diabetes 44:665-671, 1995.
19. Kristal BS, Matsuda M, Yu BP: Abnormalities in the mitochondrial permeability transition in diabetic
rats. Biochem Biophys Res Commun 222:519-523, 1996.
20. Bressler P, Bailey SR, Matsuda M, DeFronzo RA : Insulin resistance and coronary artery disease.
21. Kristal BS, Jackson CT, Chung H-Y, Matsuda M, Nguyen HC, Yu BP : Defects at center P underlie
diabetes-associated mitochondrial dysfunction. Free Radic Biol Med 22:823-833, 1997.
22. Bahl JJ, Matsuda M, DeFronzo RA, Bressler R : In vitro and in vivo suppression of gluconeogenesis by
inhibition of pyruvate carboxylase. Biochem Pharmacol 53:67-74, 1997.
23. Del Prato S, Matsuda M, Simonson DC, Groop LC, Sheehan P, Leonetti F, Bonadonna RC, DeFronzo
RA: Studies on the mass action effect of glucose in NIDDM and IDDM: evidence for glucose resistance.
24. Matsuda M, Mandarino L, DeFronzo RA : Synergistic interaction of magnesium and vanadate on
glucose metabolism in diabetic rats. Metabolism 48:725-731, 1999.
25. Matsuda M, Liu Y, Mahankali S, Pu Y, Mahankali A, Wang J, DeFronzo RA, Fox PT, Gao JH : Altered
hypothalamic function in response to glucose ingestion in obese humans. Diabetes 48:1801-1806,
26. Matsuda M, DeFronzo RA : Insulin sensitivity indices obtained from oral glucose tolerance testing:
comparison with the euglycemic insulin clamp. Diabetes Care 22:1462-1470, 1999.
27. Pijl H, Ohashi S, Matsuda M, Miyazaki Y, Mahankali A, Kumar V, Pipek R, Iozzo P, Lancaster JL,
Cincotta AH, DeFronzo RA : Bromocriptine: a novel approach to the treatment of type 2 diabetes. Diabetes Care 23:1154-1161, 2000.
28. Kaku K, Matsuda M, Urae A, Irie S : Pharmacokinetics and pharmacodynamics of insulin aspart, a
rapid-acting analog of human insulin, in healthy Japanese volunteers. Diabetes Res Clin Pract 49:119-126, 2000.
29. Iozzo P, Pratipanawatr T, Pijl H, Vogt C, Kumar V, Pipek R, Matsuda M, Mandarino LJ, Cusi KJ,
DeFronzo RA : Physiological hyperinsulinemia impairs insulin-stimulated glycogen synthase activity
and glycogen synthesis. Am J Physiol Endocrinol Metab 280:E712-E719, 2001.
30. Miyazaki Y, Glass L, Triplitt C, Matsuda M, Cusi K, Mahankali A, Mahankali S, Mandarino LJ,
DeFronzo RA : Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type II
diabetic patients. Diabetologia 44:2210-2219, 2001.
31. Miyazaki Y, Mahankali A, Matsuda M, Glass L, Mahankali S, Ferrannini E, Cusi K, Mandarino LJ,
DeFronzo RA : Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects
treated with pioglitazone. Diabetes Care 24:710-719, 2001.
32. Miyazaki Y, Matsuda M, DeFronzo RA : Dose-response effect of pioglitazone on insulin sensitivity and
insulin secretion in type 2 diabetes. Diabetes Care 25:517-523, 2002.
33. Eto M, Saito M, Okada M, Kume Y, Kawasaki F, Matsuda M, Yoneda M, Matsuki M, Takigami S, Kaku
K : Apolipoprotein E genetic polymorphism, remnant lipoproteins, and nephropathy in type 2 diabetic patients. Am J Kidney Dis 40:243-251, 2002.
34. Miyazaki Y, Mahankali A, Matsuda M, Mahankali S, Hardies J, Cusi K, Mandarino LJ, DeFronzo RA :
Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab 87:2784-2791, 2002.
35. Matsuda M, DeFronzo RA, Glass L, Consoli A, Giordano M, Bressler P, Del Prato S : Glucagon dose
response curve for hepatic glucose production and glucose disposal in type 2 diabetic patients and normal individuals. Metabolism 51:1111-1119, 2002.
36. Matsuda M, Kawasaki F, Mikami Y, Takeuchi Y, Saito M, Eto M, Kaku K : Rescue of beta-cell
exhaustion by diazoxide after the development of diabetes mellitus in rats with streptozotocin induced
diabetes. Eur J Pharm 453:141-148, 2002.
37. Gastaldelli A, Miyazaki Y, Pettiti M, Matsuda M, Mahankali S, Santini E, DeFronzo RA, Ferrannini
E : Metabolic effects of visceral fat accumulation in type 2 diabetes. J Clin Endocrinol Metab.
38. Lee NA, Matsuda M, Bressler P, Pratipanawatr T, Glass L, Mandarino LJ, DeFronzo RA : Effect of
misoprostol (PGE1) on glucose metabolism in type 2 diabetic and control subjects. Diabetes Obes
39. Ferrannini E, Gastaldelli A, Matsuda M, Miyazaki Y, Pettiti M, Glass L, DeFronzo RA.: Influence of
ethnicity and familial diabetes on glucose tolerance and insulin action: a physiological analysis. J
40. Ferrannini E, Gastaldelli A, Miyazaki Y, Matsuda M, Pettiti M, Natali A, Mari A, DeFronzo RA.:
Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in impaired glucose
tolerance. Diabetologia. 46:1211-9, 2003.
41. Gastaldelli A, Ferrannini E, Miyazaki Y, Matsuda M, DeFronzo RA.: Beta-cell dysfunction and glucose
intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia. 47:31-9, 2004.
42. Kaku K, Kawasaki F, Kanda Y, Matsuda M : Retained capacity of glucose-mediated insulin secretion in
patients with type 2 diabetes mellitus inversely correlates with the duration of diabetes. Diabetes Res
43. Hamano M, Saito M, Eto M, Suda H, Matsuda M, Matsuki M, Yamamoto S, Kaku K: Serum smyroid A
(SAA), C-reactive protein and remnant-like lipoprotein particles (RLP)-cholesterol in type 2 diabetic
patients with coronary heart disease. Ann. Clin. Biocem. 41(Pt 2):125-9, 2004.
44. M. Matsuda, F. Kawasaki, K. Yamada Y. Kanda, M. Saito, M. Eto, M. Matsuki, and K. Kaku: Impact of
Adiposity and Plasma Adipocytokines on Diabetic Angiopathies in Japanese Type 2 Diabetic Subjects.
45. Saito M, Eto M, Nitta H, Kanda Y, Shigeto M, Nakayama K, Tawaramoto K, Kawasaki F, Kamei S,
Kohara K, Matsuda M, Matsuki M, Kaku K.: Effect of apolipoprotein E4 allele on plasma LDL
cholesterol response to diet therapy in type 2 diabetic patients. Diabetes Care. 27:1276-80, 2004.
46. Kanazawa A, Tsukada S, Sekine A, Tsunoda T, Takahashi A, Kashiwagi A, Tanaka Y, Babazono T,
Matsuda M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S.: Association of the
Gene Encoding Wingless-Type Mammary Tumor Virus Integration-Site Family Member 5B (WNT5B) with Type 2 Diabetes. Am J Hum Genet. 75:832-43, 2004.
47. Ferrannini E, Gastaldelli A, Miyazaki Y, Matsuda M, Mari A, Defronzo RA.: -Cell function in subjects
spanning the range from normal glucose tolerance to overt diabetes: a new analysis. J Clin Endocrinol
48. Fumiko Kawasaki, Masafumi Matsuda, Yukiko Kanda, Hiroshi Inoue, and Kohei Kaku: Structural and
functional analysis of pancreatic islets preserved by pioglitazone in db/db mice. Am J Physiol
49. Shimazaki A, Kawamura Y, Kanazawa A, Sekine A, Saito S, Tsunoda T, Koya D, Babazono T, Tanaka Y,
Matsuda M, Kawai K, Iiizumi T, Imanishi M, Shinosaki T, Yanagimoto T, Ikeda M, Omachi S,
Kashiwagi A, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakajima M, Nakamura Y, Maeda S.:
Genetic Variations in the Gene Encoding ELMO1 Are Associated With Susceptibility to Diabetic Nephropathy. Diabetes. 54:1171-8, 2005.
50. Maeda S, Tsukada S, Kanazawa A, Sekine A, Tsunoda T, Koya D, Maegawa H, Kashiwagi A, Babazono
T, Matsuda M, Tanaka Y, Fujioka T, Hirose H, Eguchi T, Ohno Y, Groves CJ, Hattersley AT, Hitman GA, Walker M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Kamatani N, McCarthy MI, Nakamura
Y.: Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus. J
51. Kanazawa A, Kawamura Y, Sekine A, Iida A, Tsunoda T, Kashiwagi A, Tanaka Y, Babazono T, Matsuda
M, Kawai K, Iiizumi T, Fujioka T, Imanishi M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R,
Nakamura Y, Maeda S.: Single nucleotide polymorphisms in the gene encoding Kruppel-like factor 7 are associated with type 2 diabetes. Diabetologia. 48:1315-22, 2005.
52. Saito M, Kuratsune H, Nitta H, Kawahara K, Hamano M, Matsuda M, Kaku K, Eto M.: Plasma lipid
levels and nutritional intake in childhood- and adolescence-onset young type 1 diabetic patients in
Japan. Diabetes Res Clin Pract. 73:29-34, 2006.
53. Shigeto M, Katsura M, Matsuda M, Ohkuma S, Kaku K.: First phase of glucose-stimulated insulin
secretion from MIN 6 cells does not always require extracellular calcium influx. J Pharmacol Sci.
54. Gastaldelli A, Ferrannini E, Miyazaki Y, Matsuda M, Mari A, Defronzo RA.: Thiazolidinediones
Improve Beta-Cell Function in Type 2 Diabetic Patients. Am J Physiol Endocrinol Metab. 292:E871-83,
55. Abdul-Ghani MA, Matsuda M, Balas B, DeFronzo RA.: Muscle and liver insulin resistance indexes
derived from the oral glucose tolerance test. Diabetes Care 30:89-94, 2007.
56. Shigeto M, Katsura M, Matsuda M, Ohkuma S, Kaku K.: Nateglinide and mitiglinide, but not
sulfonylureas, induce insulin secretion through a mechanism mediated by calcium release from
endoplasmic reticulum. J Pharmacol Exp Ther. 322:1-7, 2007.
57. Matsuki M, Matsuda M, Kohara K, Shimoda M, Kanda Y, Tawaramoto K, Shigetoh M, Kawasaki F,
Kotani K, Kaku K.: Pharmacokinetics and pharmacodynamics of glimepiride in type 2 diabetic
patients: compared effects of once- versus twice-daily dosing. Endocr J. 54:571-6, 2007.
58. Jani R, Molina M, Matsuda M, Balas B, Chavez A, DeFronzo RA, Abdul-Ghani M.: Decreased
non-insulin-dependent glucose clearance contributes to the rise in fasting plasma glucose in the
nondiabetic range. Diabetes Care 31:311-5, 2008.
59. Abdul-Ghani M, Matsuda M, Jani R, Jenkinson CP, Richardson DK, Kaku K, Defronzo RA.: The
relationship between fasting hyperglycemia and insulin secretion in subjects with normal or impaired
glucose tolerance Am J Physiol Endocrinol Metab. 295:E401-6, 2008.
60. Kanda Y, Matsuda M, Tawaramoto K, Kawasaki F, Hashiramoto M, Matsuki M, Kaku K.: Effects of
sulfonylurea drugs on adiponectin production from 3T3-L1 adipocytes: implication of different
mechanism from pioglitazone. Diabetes Res Clin Pract. 81:13-8, 2008.
61. Makoto Shigeto, Masashi Katsura, Masafumi Matsuda, Ohkuma Seitaro, Kohei Kaku: Low, but
physiological, concentration of GLP-1 stimulates insulin secretion independent of the cAMP-dependent
protein kinase pathway. J Pharmacol Sci. 108(3):274-9, 2008. Epub 2008 Nov 6.
62. Abdul-Ghani MA, Matsuda M, DeFronzo RA.: Strong association between insulin resistance in liver
and skeletal muscle in non-diabetic subjects. Diabet Med. 25:1289-94, 2008.
English Review 1. DeFronzo RA, Matsuda M, Barrett EJ: Diabetic ketoacidosis; A combined metabolic- nephrologic
approach to therapy. Diabetes Reviews 2:209-238, 1994.
Letter, Proceedings 1. Matsuda M, DeFronzo RA: Insulin Sensitivity Indexes Calculated From Oral Glucose Tolerance Test
Data; Response to Belfiore. Diabetes Care 23:1595-1596, 2000.
2. Liu Y, Fox PT, Liu H-L, Mao J, Matsuda M, Gao J-H : Temporal clustering analysis for tracing the
maximal fMRI response in human brain. Proc Intl Soc Mag Reson Med 8:238 2000.
3. Saito M, Eto M, Okada M, Kawasaki F, Takeuchi Y, Matsuda M, Kaku K: Role of remnant-like
particles (RLPs) from diabetic patients on cholesteryl ester synthesis. In Shichiri M, Chinn SH, Hotta N
(Eds) Diabetes mellitus: Recent Advances for the 21st Century, Elsevier (Amsterdam, Netherlands) pp.201㹼 204, 2000.
4. Okada M, Eto M, Saito M, Kawasaki F, Takeuchi Y, Matsuda M, Kaku K.: Responses of plasma
triglyceride to fat load in type 2 diabetic patients with normal triglyceride level. In Shichiri M, Chinn SH, Hotta N (Eds) Diabetes mellitus: Recent Advances fro the 21st Century, Elsevier (Amsterdam,
5. M Matsuda, F Kawasaki, H Inoue, Y Kanda, K Yamada, Y Harada, M Saito, M Eto, M Matsuki, and K
Kaku: Possible Contribution Of Adipocytokines On Diabetic Neuropathy (Presented at the 12th
Japan-Korea Symposium on Diabetes Mellitus on May 9, 2003 in Nagoya, Japan) Diabetes Res Clin
6. Gastaldelli A, Ferrannini E, Miyazaki Y, Matsuda M, DeFronzo RA: Reply to Comment on: Beta cell
dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study.
7. Matsuda M, Kawasaki F, Inoue H, Kanda Y, Yamada K, Harada Y, Saito M, Eto M, Matsuki M, Kaku K.:
Possible contribution of adipocytokines on diabetic neuropathy. Diabetes Res Clin Pract. 66 Suppl
8. Kanda Y, Matsuda M, Hamamoto S, Kawasaki F, Kotani K, Matsuki M, Kaku K.: Analysis of waist
circumference in Japanese subjects with type 2 diabetes mellitus: lack of propriety to define the current
criteria of metabolic syndrome.Diabetes Res Clin Pract. 77 Suppl 1:S220-3, 2007.
Meetings 1. Matsuda M, Matsutani A, Kaku K, Kaneko T: Sulfonylurea regulation of acetyl-CoA carboxylase in rat
adipocytes 13th International Diabetes Federation Congress (Sydney, Australia) 1988 11.20-25.
2. Matsuda M, Banduch D, Bressler R: Mechanism of Action of Hydrocinnamic Acid 52nd Scientific
Sessions of American Diabetes Association (San Antonio, USA) 1992 6.20-23 Diabetes 41 (suppl. 1):
3. Matsuda M, Consoli A, Bressler P, DeFronzo RA, Del Prato S: Sustained Response of Hepatic Glucose
Production (HGP) to Glucagon in Type 2 Diabetic Subjects 28th Annual Meeting of European
Association for the Study of Diabetes (Prague, Czechoslovakia) 1992 9.8-11 Diabetologia 35 (suppl. 1):
4. Matsuda M, Banduch D: Effect of IGF-I on Protein Metabolism in Diabetic and ControlRats 53rd
Scientific Sessions of American Diabetes Association (Las Vegas, USA) 1993 5.12-15 Diabetes 42 (suppl. 1): 39A, 1993.
5. Matsuda M, Shank M, Malasanos TH, Mandarino L: Effect of Free Fatty Acid (FFA) on Intracellular
Glucose Oxidation (GOX) and Glycogen Synthesis (GS) in NIDD subjects 54th Scientific Sessions of
American Diabetes Association (New Orleans, USA) 1994 6.11-14 Diabetes 43 (suppl. 1): 49A, 1994.
6. Matsuda M, Banduch D, DeFronzo RA: Effect of Magnesium Vanadate (MgV) on Glucose Metabolism in
Normal and STZ-induced Diabetic Rats 15th International Diabetes Federation Congress (Kobe,
7. Matsuda M, Lee N, Shank ML: Increased Hepatic Glucose Production in Subjects with Family History
of NIDDM 55th Scientific Sessions of American Diabetes Association (Atlanta, USA) 1995 6.10-13 Diabetes 44 (suppl. 1): 108A, 1995.
8. Matsuda M, Lee N, Shank M, DeFronzo RA: Isolation of Hepatic and Peripheral Insulin Sensitivity:
Application to the Investigation of Inherited or Acquired Defects in NIDDM 56th Scientific Sessions
of American Diabetes Association (San Francisco, USA) 1996 6.8-11 Diabetes 45 (suppl. 1): 17A, 1996.
9. Matsuda M, Sugaya K, Mandarino LJ, Marusawa H, DeFronzo RA: Abnormal vitamin D binding
protein fragment in blood of first degree relatives of patients with type 2diabetes mellitus 16th International Diabetes Federation Congress (Helsinki, Finnland) 1997 7.20-25 Diabetologia 40 (suppl.
10. Matsuda M, DeFronzo RA: Relationship between insulin sensitivity in adipose tissue, liver, muscle, and
components of the insulin resistance syndrome 57th Scientific Sessions of American Diabetes
Association (Boston, USA) 1997 6.21-24 Diabetes 46 (suppl. 1): 68A, 1997.
11. Matsuda M: Synergistic effect of Magnesium and Vandate on Insulin Action in Nondiabetic and Diabetic
Rats 58th Scientific Sessions of American Diabetes Association (Chicago, USA) 1998 6.13-16 Diabetes 47 (suppl. 1): A288, 1998.
12. Matsuda M, Liu Y, Mahankali S, Pu Y, Mahankali A, Wang J, DeFronzo RA, Fox PT, Gao JH: Brain
Function After glucose Intake in Obese Humans The Paraventricular Nucleus of the Hypothalamus: A
Crossroads of Integrative Physiology 1998 APS conference (San Antonio, USA) 1998 12.5-7
13. Matsuda M, Liu Y, Mahankali S, Pu Y, Mahankali, A, Wang J, DeFronzo RA, Fox PT, Gao J-H : Altered
Brain Function after Intravenous Glucose Infusion in Humans 59th Scientific Sessions of American Diabetes Association (San Diego, USA) 1999 6.19-22 Diabetes 48 (suppl. 1): A27, 1999.
14. Matsuda M, DeFronzo RA: Insulin Sensitivity Indices Obtained from Oral Glucose Tolerance Test:
Comparison with Euglycemic Insulin Clamp 59th Scientific Sessions of American Diabetes Association
(San Diego, USA) 1999 6.19-22 Diabetes 48 (suppl. 1): A79, 1999.
15. Matsuda M, Hiramatsu S, Teramoto F, Kawasaki F, Kaku K: Sparing of fat in lean female subjects with
type 2 diabetes mellitus during fasting state. 60th Scientific Sessions of American Diabetes Association (San Antonio, USA, June 10 – 13, 2000), Diabetes 49 (suppl. 1):A92, 2000.
16. Matsuda M, Kawasaki F, Takeuchi Y, Saito M, Eto M, Kaku K: Rescue of Pancreatic beta-cell
exhaustion by pharmacological intervention in STZ-induced diabetic rats 36th Annual Meeting of the
European Association for the Study of Diabetes (Jerusalem, Israel, September 17 - 21, 2000),
17. Matsuda M, Kawasaki F, Kohara K, Saito M, Yoneda M, Matsuki M, Eto M, Kaku K: Carotid
Intima-Media Thickness and Localization of Adiposity in Subjects with Type 2 Diabetes Mellitus. 61st
Scientific Sessions of American Diabetes Association (Philadelphia, USA, June 22 - 26, 2001), Diabetes 50(suppl.2): A98, 2001.
18. Matsuda M, Kawasaki F, Tamechika Y, DeFronzo RA, Kaku K: Contribution of the Pancreas,
Peripheral Tissues, and Liver in the Increment in Plasma Glucose after Oral Glucose Load 62nd
Scientific Sessions of American Diabetes Association (San Fransisco, USA, June 14- 18, 2002), Diabetes
19. M.Matsuda, F.Kawasaki, H.Inoue, K.Kaku: Effect of spironolactone on insulin sensitivity in normal and
fa/fa rats. Diabetes and Metabolism 2003. (16th International Diabetes Federation Congress, Paris, France, August 24 - 29, 2003) .
20. Masafumi Matsuda, Fumiko Kawasaki, Yukiko Kanda, Yumiko Harada, Mieko Saito, Hiroshi Inoue,
Masaaki Eto, Michihiro Matsuki, Kohei Kaku: Impact of Adipocity through Plasma Adipocytokines on
Diabetes Angiopathies in Japanese Type 2 Diabetic Subjects: Diabetes 52 (suppl 1): A161, 2003, 63th Scientific Sessions of American Diabetes Association (New Orleans, USA, June 13 - 17, 2003).
21. Masafumi Matsuda, Fumiko Kawasaki, Makoto Shigeto, Kohei Kaku: Effects of dihydropyridine
derivatives on insulin sensitivity in spontaneous hypertensive rats Diabetes 53 (suppl1): A312, 2004,
64th Sceintific Sessions of American Diabetes Association (Orlando, Florida, USA, June 4 - 8, 2004).
22. M. Matsuda, F. Kawasaki, Y. Kanda, H. Kishimoto, H. Sumiko, M. Shimoda, M. Shigeto, K. Tawaramoto,
K. Kohara, K. Nakayama, M. Matsuki, K. Kaku: Pioglitazone modifies not only distribution but also
density of adipose tissue in Type 2 diabetic patients. Diabetologia 48 (suppl 1): A279-80, 2005, 41st Annual Meeting of the European Association for the Study of Diabetes (EASD) (Athens, Greece, Sept
23. Masafumi Matsuda, Yukiko Kanda, Kohei Kaku.: Significance of Pancreatic Fat Accumulation in Type 2
Diabetic Subjects. 66th Annual Scientific Sessions of American Diabetes Association (Washington D.C.,
24. Matsuda M, Shigeto M, Akiyama Y, Masuzawa M, Okabe T: Constancy of Relative Insulin Sensitivity
and Importance of Absolute Insulin Sensitivity Shift to Develop Insulin Infusion Protocol in Critically Ill Patients. 43rd Annual Meeting of the European Association for the Study of Diabetes (EASD)
25. Matsuda M, Hisano Y, Hayakawa N, Shigeto M, Akiyama Y, Masuzawa M, Okabe T: Difference between
Insulin Sensitivity Expressed by Ability to Lower Plasma Glucose Concentration and to Keep Plasma Glucose Concentration Stable during Medical Treatment. 44th Annual Meeting of the European
Association for the Study of Diabetes (EASD) (Rome, Italy, 2008).
Nicholas Sitar Nick Sitar received his undergraduate degree in Geological Engineering from the University of Windsor in Windsor, Ontario in 1973, and his Ph.D. in Geotechnical Engineering from Stanford University in 1979. After receiving his Ph.D., he spent two years teaching in the Geological Engineering Program at the University of British Columbia in Vancouver, B.C. He joined the
Wechselwirkungen zwischen ART und Antidepressiva Trizyklische Antidepressiva (TCA) besitzen eine geringe therapeutische Breite, so dass Spiegel schnel den toxischen Bereich erreichen können. Liegen die Spiegel im toxischen Bereich können u.a. kardiale Arrhythmien, anticholinerge Effekte, Sedation und Verwirrtheit auftreten. Da das HI-Virus die Basalganglien angreift und selbst anticholi