SUNDAY, June 23 17:00 – 18:00
Slovak Society for Neuroscience Committee Meeting
Symposium Venue – Catholic University, Hlavna 89, Kosice
MONDAY, June 24 08:00 – 08:45
Speaker Presentation Preview and Poster Display
Cell Signaling, Neurotoxicity and Neuroprotection I.
TUESDAY, June 25 08:00 – 08:45
Speaker Presentation Preview and Poster Display
Traumatic and ischemia/reperfusion injury of the CNS I.
Traumatic and ischemia/reperfusion injury of the CNS II.
Cell Signaling, Neurotoxicity and Neuroprotection II.
Cell Signaling, Neurotoxicity and Neuroprotection III.
Opera Performance – Giuseppe Verdi - Rigoletto
WEDNESDAY, June 26 08:00 – 08:45
Plasticity and Regenerability in the CNS I.
THURSDAY, June 27 08:30 – 09:15
Plasticity and Regenerability in the CNS II.
SCIENTIFIC PROGRAMME MONDAY, June 24
09:15 Preclinical and clinical utilization of neural stem cells in cell-replacement
NEURODEGENERATIVE DISEASES I.
10:00 Tau truncation – driving force of Alzheimer’s disease
10:30 Misfolded tau protein induces overexpression of Hsp27 in rat model of
10:45 Tauon as a novel force in AD pathogenesis
11:00 Regulation of UPS activity in models of protein foldopathies: focus on
Alzheimer’s and Parkinson’s diseases
Misfolded truncated tau protein influences neuron-glial interaction via regulation of the “On” and “Off” signalling molecules Zuzana Kazmerova NEURODEGENERATIVE DISEASES I.
13:00 Autonomic nervous system function as a putative biomarker for Huntington’s
13:30 Neuroprotective cell therapy in Alzheimer’s disease
13:45 Prion protein prevents heavy metals overload and protects cultured cells
against heavy metals toxicity Michal Prcina
Structural aspects of initiation and propagation of neurodegenerative processes promoted by intrinsically disordered proteins
CELL SIGNALING, NEUROTOXICITY AND NEUROPROTECTION I.
14:30 NF-kB inhibition and apoptosis in pheochromocytoma cell lines
15:00 P2X7 purinoceptor: an Achilles heel of neurons and glia
15:30 Some approaches for neuroprotection of the ischemic brain
POSTER SESSION I. 16:00 Neurodegenerative Diseases
ND-1 Cieslik M, Gasowska M, Langfort J, Kowalczyk A, Chalimoniuk M.
Biochemical and molecular alterations in young and aged brain of APP transgenic mice
ND-2 Czubowicz K, Strosznajder RP.
Sphingosine-1-phosphate and transcription regulation: from oxidative stress to neuronal death in ceramide toxicity. Implications for neurodegenerative diseases
ND-3 Majerova P, Zilkova M, Kazmerova Z, Zilka N, Novak M.
Multi-component cell model for neuron-glial interactions in Alzheimer’s disease
ND-4 Opattova A, Filipcik P, Cente M, Novak M.
Alterations of proteostasis in cellular model of tauopathy
The role of sphingosine kinases-1/sphingosino-1-phosphate in experimental model of Parkinson disease
ND-6 Salingova B, Barath P, Kovacech B, Novak M ND-7 Savotchenko A, Talnov A, Isaeva O, Isaev D.
Electrolyte therapy reduces spike-and-wave discharges in the WAG/Rij rat model of absence epilepsy
ND-8 Scholtzova H, Nehete PN, Nehete BP, Holmes A, Sabado R, Williams LE, Wisniewski T. Testing of innate immunity stimulation via tlr9 on cerebral amyloid angiopathy using non-human primates
ND-9 Valekova I, Kupcova Skalnikova H, Klima J, Juhas S, Motlik J.
Evidence of cytokine abnormalities in porcine model of Huntington’s disease
ND-10 Wilkaniec A, Czapski GA, Adamczyk A.
The role of purinergic receptors in alpha synuclein mediated mitochondrial dysfunction and dopaminergic cell death
Traumatic and Ischemia/Repefusion Injury of the CNS
TIR-1 Bonova P, Danielisova V, Nemethova M, Burda J, Gottlieb M.
Infarct evolution during permanent middle cerebral artery occlusion in rat
TIR-2 Danielisova V, Gottlieb M, Bonova P, Nemethova M, Burda J.
Delayed postconditioning after focal cerebral ischemia
TIR-3 Gedrova S, Galik J, Dubravcik M, Lievajova K, Zavodska M, Schreiberova A, Karasova M, Lukacova N. Porcine model of compression spinal cord injury and possible treatment therapies
TIR-4 Hricova L, Kisucka A, Oroszova Z, Kucharikova A, Schreiberova A, Pavel J, Lukacova N. Changes in NO-sGC-cGMP pathway following the injury of the n. phrenicus
TIR-5 Klacanova K, Pilchova I, Tatarkova Z, Chomova M, Dobrota D, Racay P.
Impact of global brain ischemia on BH3-only proteins Bad and PUMA
TIR-6 Kokosová N, Smajda B, Burda J.
Ionizing radiation is able to activate tolerance against transient cerebral ischemia in rats
TIR-7 Kucharikova A, Hricova L, Schreiberova A, Gedrova S, Zavodska M, Lukacova N. The effect of repeated baclofen treatment on motor activity and nnos-immunoreactivity in medullar gigantocellular reticular nuclei and in motoneurons of lumbar spinal cord in rats after spinal cord injury
TIR-8 Kuricova M, Ledecky V, Cizkova D, Grulova I, Slovinska L, Nagyova M.
Inosine administration in rats with spinal cord injury
TIR-9 Nemethova M, Talian I, Tkacikova S, Danielisova V, Bonova P, Gottlieb M, Burda J. Identification of proteomic changes in the rat brain hippocampus after bradykinin postconditioning
TIR-10 Oroszova Z, Hricova L, Lukacova N, Pavel J.
Role of Angiotensin II in regulation of sensory information
TIR-11 Petras M, Kovalska M, Tatarkova Z, Lehotsky J, Drgova A.
Effect of hyperhomocysteinemia on the gene expression of the nervous tissue antioxidant enzymes after induced ischemic tolerance
TIR-12 Pilchova I, Klacanova K, Stefanikova A, Klikova K, Dobrota D, Racay P. Global brain ischemia induced disturbances in ERK1/2 signalling and 26S proteasomal complex do not have impact on the level of selected proteins of Bcl-2 family
TIR-13 Saganova K, Racekova E, Galik J, Vanicky I.
Effectiveness of monotherapy with anti-inflammatory drugs following spinal cord compression injury in rat
TIR-14 Savchuk OI, Orlovsky MO, Dosenko VE, Skibo G.
Proteasome activity changes at different periods after focal ischemia
TIR-15 Schreiberova A, Sulla I, Kucharikova A, Gedrova S, Zavodska M, Martoncikova M, Galik J, Lukacova N The rat model of spinal cord compression: Development of motor and sensitive functions
TIR-16 Stojkovic T, Velimirovic M, Jevtic G, Nikolic T, Radonjic N, Petronijevic N
Effects of pretreatment with vitamins d and c on the brain gluthatione metabolism in gerbils subjected to transient global cerebral ischemia
TIR-17 Sulla I, Galik J, Lukac I, Balik V, Lukacova N, Marsala M
Traumatic spinal cord injury model in minipigs
TIR-18 Sulla I jr, Baciak L, Gedrova S, Zavodska M, Juranek I, Sulla I.
Functional and MRI Correlates of Spinal Cord Compression Injury in Minipigs
Autonomic nervous system response to elevated ambient temperature
TIR-20 Velimirovic M, Jevtic G, Stojkovic T, Radonjic N, Nikolic T, Petronijevic N.
The effects of vitamin D3 and dehydroascorbic acid on oxidative stress parameters in the brain of gerbils exposed to transient global cerebral ishemia
TIR-21 Zavodska M, Galik J, Pavel J, Marsala M, Gedrova S, Sulla I jr, Ledecky V, Trbulova A, Capik I, Karasova M, Sulla I, Reichel P, Gajdos M, Lukac I, Kafka J, Schreiberova A, Kucharikova A, Martoncikova M, Fabianova K, Racekova E, Juhas S, Juhasova J, Motlik J, Lukacova N. Experimental hypothermic neuroprotection after traumatic spinal cord injury
Cell Signaling, Neurotoxicity and Neuroprotection
SNN-1 Babets YV, Pierzynowski SG, Ushakova GA.
The distribution of S100b in the rat brain under experimental anthracycline therapy
SNN-2 Gottlieb M, Bonova P, Danielisova V, Nemethova M, Burda J, Matute C, Moreno B. Effect of methylthioadenosine on two models of cerebral ischemia in the rat
SNN-3 Jevtic G, Radonjic N, Velimirovic M, Stojkovic T, Petronijevic N.
The expression of neuronal and glial markers in animal models of schizophrenia
SNN-4 Khomula E, Borisyuk A, Viatchenko-Karpinski V, Belan P,Voitenko N.
Specific changes in slow and fast T-type calcium currents are associated with positive and negative types of STZ-diabetic neuropathy
TUESDAY, June 25
TRAUMATIC AND ISCHEMIA/REPERFUSION INJURY OF THE CNS I.
09:00 Angiotensin II AT1 receptor blockers as treatments for inflammatory brain
09:30 Mechanisms involved in ischemic tolerance: effect of homocysteine
TRAUMATIC AND ISCHEMIA/REPERFUSION INJURY OF THE CNS II.
10:15 Delayed remote ischemic postconditioning is knocking on the clinician’s doors
10:45 Miniature pig as a large animal model for spinal cord injury studies
11:15 Traumatic and non traumatic comatose states in ICU, prognostic oGCS value
for further quality of life Beata Saniova CELL SIGNALING, NEUROTOXICITY AND NEUROPROTECTION II.
13:00 Neurovascular mediated by nitric oxide in the brain: impact in aging and
alzheimer´s disease Joao Laranjinha
13:30 NO-cGMP signalling in respiratory pathway
CELL SIGNALING, NEUROTOXICITY AND NEUROPROTECTION III.
14:15 Does Chronic or Repeated Stress Produce Pathological Changes in the
Organism: Effect of Catecholaminergic Systems Richard Kvetnansky
14:45 Gating of neuronal CaV2.2 channels is affected by Tetraspanin-13
15:00 Possible contribution of Bcl-2 proteins in neuronal death following transient
global brain ischemia Peter Racay POSTER SESSION II. 15:15 Cell Signaling, Neurotoxicity and Neuroprotection
SNN-5 Knapp L, Kocsis K, Kovacs-Öller T, Gellert L, Varga D, Ozsvar A, Kis Z, Völgyi B, Toldi J, Farkas T. Mechanisms involved in kainic acid-induced postconditioning after global ischemia in rat hippocampus
SNN-6 Kocsis K, Knapp L, Kovacs-Öller T, Gellert L, Olah G, Heredi J, Menyhart A, Kis Zs, Völgyi B, Toldi J, Farkas T. Combination of oxaloacetate and acetyl-L-carnitine posttreatment prevents functional impairment in the hippocampus after global hypoperfusion
SNN-7 Lubina-Dabrowska N, Tomczykiewicz K, Langfort J, Stepien A, Chalimoniuk M. Effect of interferon beta on the regulation of NO/GC/cGMP pathway in brain cortex rats with experimental autoimmune encephalomyelitis (EAE)
SNN-8 Murin R, Skovierova H, Mahmood S, Causov O, Schubert A, Hatok J.
Toxicity of methanol and its metabolites on cultured glial and neuronal cell lines
SNN-9 Nagyova M, Slovinska L, Grulova I, Kafka J, Kuricova M, Ledecky V, Cizek M, Cizkova D. Assessment of membrane and nuclear labeling methods of the rat bone marrow mesenchymal stem cells in vitro
SNN-10 Pavlik A, Alrumh M, Alexander G.
Hyperthermia-induced tolerance to excitotoxic hippocampal damage: role of non-neuronal hsp70
SNN-11 Petronijevic N, Jevtic G, Vucetic-Arsic S, Jovanovic M, Selakovic V, Nikolic T, Velimirovic M, Stojkovic T, Radonjic N. NADPH-oxidase expression in the brain of gerbils treated with aluminum
SNN-12 Smajda B, Kokosova N, Tomasova L.
Effects of prenatal irradiation with gamma-rays on adult hippocampal neurogenesis and behaviour in rats
Plasticity and Regenerability in th CNS
PR-1 Babic S, Danevova V, Pokusa M, Jezova D.
Stress-induced reduction of cell proliferation in the hippocampus is not modified by treatment with oxytocin antagonist atosiban
PR-2 Blasko J, Lievajova K, Martoncikova M, Racekova E.
Morphological basis for potential neuronal regulation of postnatal neurogenesis in the rat rostral migratory stream
PR-3 Devaux S, Cizkova D, Marrec-Croq FL, Franck J, Slovinska L, Grulova I, Lefebvre Ch, Fournier I, Salzet M. Proteomic analyses along the rostro-caudal axis of injured spinal cord
PR-4 Fabianova K, Blasko J, Martoncikova M, Racekova E.
Various odor stimuli affect the distribution of Fos positive cells in the olfactory system neurogenic area of the rat
PR-5 Goncharova K, Osadchenko I, Kovalenko T, Pierzynowski S, Skibo G.
PR-6 Hvizdosova N, Tomasova L, Bolekova A, Kolesar D, Kluchova D.
Postnatal development of nitrergic neurons in the rat prefrontal cortex
PR-7 Kutna V, Sevc J, Matiasova A, Gombalova Z, Daxnerova Z.
Enigmatic cerebrospinal fluid-contacting neurons arise even after the termination of neurogenesis in the spinal cord of rat during the embryonic development and retain their immature-like characteristics until adulthood
PR-8 Martoncikova M, Fabianova K, Blasko J, Schreiberova A, Racekova E.
Arrangement of blood vessels, neuroblasts and astrocytes in the rostral migratory stream of adult rats
PR-9 Matiasova A, Sevc J, Kutna V, Gedrova S, Daxnerova Z.
Proliferating radial glial cells in the central canal lining of rat spinal cord are the source of migrating glial cells with non-ependymal phenotype during the postnatal development
PR-10 Sevc J, Kutna V, Matiasova A, Daxnerova Z.
Ventricular zone of the spinal cord is the source of cells with oligodendroglial phenotype even during postnatal development and in adulthood in intact rat
PR-11 Tomasova L, Hvizdosova N, Kolesar D, Bolekova A, Smajda B, Kluchova D.
Emotional behaviour and amygdala after prenatal exposure to retinoic acid
Clinical Neuroscience
CN-1 Balik V, Trojanec R, Holzerova M, Tuckova L, Sulla I, Kneblova M, Vaverka M, Hrabalek L, Ehrmann J. A Comparative Genomic/Fluorescent In Situ Hybridization and Immunohistochemical Study of Adult Multifocal Medulloblastoma with Diffuse Acute Postoperative Cerebellar Swelling
Bolekova A, Tomasova L, Hvizdosova N, Lovasova K, Kluchova D. Influence of retinoic acid on postnatal development of hippocampal neurons in the rat
CN-3 Cierny D, Michalik J, Dobrota D, Lehotsky J.
Association study of the inflammatory gene polymorphisms in the clinical course of multiple sclerosis
Dalm B, Viljoen S, Reddy Ch, Wilson S, Gilles GT, Hitchon P, Howard M. A Novel Intradural Spinal Cord Stimulation Device
Dorko F, Horacek J, Tokarcik J, Sulla I. Neuro-vascular relationship in avian bursa cloacalis (Fabricii)
Furdova A, Sramka M, Chorvath M, Kralik G, Trompak O. Stereotactic radiosurgery in treatment of benign intraocular tumor
Furdova A, Sramka M, Chorvath M, Kralik G, Trompak O. Visual acuity decline in patients with posterior uveal melanoma after stereotactic radiosurgery
Galbavy S, Palkovic M, Sramka M, Galbavy A, Sidlo J. Clinical and pathologic identification of creutzfeldt jakob disease in Slovakia
Galbavy S, Sramka M, Galbavy A, Sidlo .J Isolated intracranial rosai-dorfman disease – report of case
CN-10 Chalimoniuk M, Lukacova N, Chrapusta SJ, Langfort J.
Endurance training enhances the activity of the NOS/GC/cGMP pathway in the striatum, midbrain and cerebellum in healthy young adult rats
Intradural extramedullary spinal tumors
CN-12 Richterova R, Bittsansky M, Ilovska V, Jurecekova J, Kolarovszki B, De Riggo J, Sutovsky J, Benco M , Racay P, Polacek H , Dobrota D. Our experiences with MR spectroscopy in brain tumors
CN-13 Sramka M, Chorvath M, Kralik G, Galbavy A, Furdova A.
Stereotactic radiosurgery treatment of benign intracranial meningiomas; its influence on patient´s health and his life
CN-14 Tukaiev S, Zima I, Krizhanovskiy S, Piskorska N, Radchuk O.
Assessment of the effects of aversive chemosensory stimuli
CN-15 Tymchenko S, Negerish A, Evstafyeva E.
Functional antagonism between zinc, copper and lead related to heart rate variability
CN-16 Zavgorodnya K, Tymchenko S.
Relationship of Aggression to Autonomic Regulation of Heart Rate Variability
WEDNESDAY, June 26 PLASTICITY AND REGENERABILITY IN THE CNS I.
09:00 Multiple changes in peptide and lipid expression associated with regeneration
in the nervous system of the medicinal leech: Focus on microglial cells role
09:30 Plasticity of hippocampal cells in ischemic brain
CLINICAL NEUROSCIENCE I.
10:15 Carotid surgery for stroke prevention in the USA 2013
10:45 Influence of deep cerebellar stimulation on electroencephalographic activity
THURSDAY, June 27 PLASTICITY AND REGENERABILITY IN THE CNS II.
09:30 The influence of sustained EGF and bFGF release on the expansion and
differentiation of neural progenitors in affinity-binding alginate scaffolds
10:00 Regenerative potential of platelet-rich plasma and mesenchymal stem cells
and their applicability in medicine Timea Spakova
10:15 Phenotyping of neural progenitor cells derived from different developmental
stages of CNS: in vitro study Lucia Slovinska CLINICAL NEUROSCIENCE II.
10:45 Decompressive craniotomy in severe brain trauma
11:15 Discogennic Cauda Equina Syndrome – Clinical and Experimental Study
11:30 Linear accelerator based stereotactic radiosurgery for posterior uveal
melanoma - our experience Alena Furdova
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