Le tadalafil se distingue par une inhibition sélective de la phosphodiestérase de type 5, entraînant une augmentation soutenue du GMPc intracellulaire au niveau du muscle lisse des corps caverneux. Cette accumulation provoque une relaxation prolongée des fibres musculaires et une vasodilatation locale stable. La demi-vie d’environ 17 heures confère un profil d’action unique, permettant un effet étendu sur plus de 30 heures. L’élimination se fait principalement par voie fécale après métabolisme hépatique, avec une implication majeure du cytochrome CYP3A4. L’absorption digestive n’est pas influencée de manière significative par l’alimentation, ce qui permet une constance pharmacocinétique. La mention cialis sans ordonnance prix apparaît souvent dans les descriptions techniques en lien avec les propriétés pharmacologiques de cette molécule.

18110p03.doc

New York State Office Of General Services
Procurement Services Group
Corning Tower Building
Empire State Plaza
Albany, New York 12242
http://www.ogs.state.ny.us
PURCHASING MEMORANDUM

AWARD NUMBER:
PLEASE ADDRESS INQUIRIES TO:
GROUP: 10200 - Pharmaceutical
STATE AGENCIES & CONTRACTORS
CONTRACT PERIOD: May 1, 2003 -
CONTRACTOR:
CONTRACT NO.:

SUBJECT: Price List Update

TO DEPT. OF CORRECTIONAL SERVICES CENTRAL PHARMACY:

GlaxoSmithKline has offered, and we have accepted, prices to reflect their new contract prices effective TRADE DESCRIPTION
PACKAGING
CONTRACT
GROUP 10200 - Pharmaceutical, Dept. of Correctional Services Central Pharmacy
Please note that the prices for Engerix B , Havrix and Twinrix vaccines do not include the Federal Excise Tax of $0.75
per antigen, per dose.
New York State Office Of General Services
Procurement Services Group
Corning Tower Building
Empire State Plaza
Albany, New York 12242
http://www.ogs.state.ny.us
PURCHASING MEMORANDUM

AWARD NUMBER:
PLEASE ADDRESS INQUIRIES TO:
GROUP: 10200 - Pharmaceutical
STATE AGENCIES & CONTRACTORS
CONTRACT PERIOD: May 1, 2003 -
CONTRACTOR:
CONTRACT NO.:

SUBJECT: Contract Update

TO DEPT. OF CORRECTIONAL SERVICES CENTRAL PHARMACY:

GlaxoSmithKline has offered, and we have accepted, prices to reflect their new contract prices effective May 1, 2004 as follows:

LOT III
Contract Period
May 1, 2004 - April 30, 2005
PRODUCT LINE:
GlaxoSmithKline
CONTRACT
TRADE DESCRIPTION
PACKAGING
AUGMENTIN XR TABLETS SCORED 1000MG 40S 40EAx1 GROUP 10200 - Pharmaceuticals, Dept. of Correctional Service Central Pharmacy

Notwithstanding of the prices listed on the above exhibit, the prices of products with double asterisks (**) on
the Product and Price Exhibits shall remain equal to the Wholesaler Acquisition Cost (WAC) throughout the
term hereof. In the event of a change by GSK in such product’s Wholesaler Acquisition Cost, the product’s
contract price shall immediately, automatically, and without notice, be changed to equal such product’s
WAC price.
Please note that the prices for Engerix B®, and Twinrix ® vaccines do not include the Federal Excise Tax of
$0.75 per antigen, per dose.

All terms and conditions remain unchanged. Should you have any questions concerning this Purchasing Memorandum, please call this office at 518/474-0912 or e-mail donna.mcneil@ogs.state.ny.us.

Source: http://www.ogs.state.ny.us/purchase/spg/pdfdocs/1020018110p.pdf