PREFERRED DRUG LIST Effective October 2013 – March 2014 PREFERRED ALTERNATIVES
NCE DEXILANT#, lansoprazole#, omeprazole#, pantoprazole#
NCE benzoyl peroxide products*, topical tretinoin*, topical clindamycin*
ASMANEX#, FLOVENT#, PULMICORT FLEXHALER#, QVAR#
DIOVAN#, candisartan#,irbesartan#, lisinopril, losartan#, quinapril
NC DIOVAN HCT#, irbesartan/HCTZ#, lisinopril/HCTZ, losartan/HCTZ#, quinapril/HCTZ
naratriptan#, RELPAX#, rizatriptan#, sumatriptan#, zolmitriptan#
NCE benzoyl peroxide products*, topical tretinoin*, topical clindamycin*
DIOVAN#, candisartan#, irbesartan#, lisinopril, losartan#, quinapril
DIOVAN HCT#, irbesartan/HCTZ#, lisinopril/HCTZ, losartan/HCTZ#, quinapril/HCTZ
diclofenac, ibuprofen, meloxicam#, nabumetone
NC cetirizine# (OTC), desloratadine#*, levocetirizine#*, loratadine# (OTC)
NCE cetirizine# (OTC), levocetirizine#*, loratadine# (OTC)
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter; P = Preferred drug; N = Non-Preferred drug UPPERCASE = BRAND; lowercase = generic ^ May require Prior Authorization for some plans NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
PREFERRED ALTERNATIVES
(CONCERTA)#*, methylphenidate/ext-rel#, mixed salts amphetamines ext-rel#*
divalproex sodium/divalproex sodium ext-rel
granisetron#, metoclopramide, ondansetron#
DETROL LA, oxybutynin ext-rel, tolterodine, trospium, VESICARE
RELPAX#, naratriptan#, rizatriptan#, sumatriptan#, zolmitriptan#
atorvastatin#, CRESTOR#, fluvastatin#, lovastatin#, simvastatin#
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter; P = Preferred drug; N = Non-Preferred drug UPPERCASE = BRAND; lowercase = generic ^ May require Prior Authorization for some plans NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
PREFERRED ALTERNATIVES
(CONCERTA)#*, methylphenidate ext-rel#, mixed salts amphetamines ext-rel#*
DIOVAN#, candisartan#, irbesartan#, lisinopril, losartan#, quinapril
DIOVAN HCT#, irbesartan/HCTZ#, lisinopril/HCTZ, losartan/HCTZ#, quinapril/HCTZ
NCE DEXILANT#, lansoprazole#, omeprazole#, pantoprazole#
OMEPRAZOLE/SODIUM BICARBONATE 40-1100 MG NCE DEXILANT#, lansoprazole#, omeprazole#, pantoprazole#OMNARIS#
DEXILANT#, lansoprazole#, omeprazole#, pantoprazole#
NCE DEXILANT#, lansoprazole#, omeprazole#, pantoprazole#
flunisolide#, fluticasone#, NASONEX#, triamcinolone nasal spray#
NC methylphenidate ext-rel (CONCERTA)#*, methylphenidate ext-rel#
NC Amethia (3 copayments), Camrese (3 copayments)
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter; P = Preferred drug; N = Non-Preferred drug UPPERCASE = BRAND; lowercase = generic ^ May require Prior Authorization for some plans NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
PREFERRED ALTERNATIVES
benazepril, enalapril, lisinopril, quinapril, trandolapril
benazepril/HCTZ, enalapril/HCTZ, lisinopril/HCTZ, quinapril/HCTZ, trandolapril/HCTZ
DETROL LA, oxybutynin ext-rel, tolterodine, trospium, VESICARE
NC alfuzosin ext-rel, doxazosin, tamsulosin, terazosin
NCE DEXILANT#, lansoprazole#, omeprazole#, pantoprazole#
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter; P = Preferred drug; N = Non-Preferred drug UPPERCASE = BRAND; lowercase = generic ^ May require Prior Authorization for some plans NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
SPECIALTY DRUG LIST
The following is the Specialty Drug List, many of the drugs are oral tablets or self administered while some drugs (in bold type) are typically provided within a physician office setting with coverage under the medical benefit. For members with a specialty benefit, coverage for drugs listed in bold type wil not be provided under the medical benefit. Providers must obtain these products through a preferred specialty vendor. Medications noted with a ^ below may require prior authorization. Medications with a # may be subject to quantity limits. Please refer to www.bcbsri.com for more detailed program benefit information. DRUG CATEGORY SPECIALTY MEDICATION/HIGHEST TIER ANTI-INFECTIVE Antivirals, Hepatitis C Incivek
Infergen (interferon alfacon-1) Intron A (interferon alfa 2b) Pegasys (peginterferon alfa 2a)^ PegIntron (peginterferon alfa 2b)^ PegIntron Redipen (peginterferon alfa 2b)^ Victrelis (boceprevir)^#
HIV, AIDS DERMATOLOGY Psoriasis
Enbrel (etanercept)^# PREFERRED self administered Humira (adalimumab)^# PREFERRED self administered Remicade (infliximab)^ PREFERRED provider administered Stelara (ustekinumab)^ PREFERRED provider administered ENDOCRINE Growth Hormone Products Genotropin
Humatrope (somatropin)^# Increlex (mecasermin)^ Norditropin (somatropin)^# Norditropin Nordiflex (somatropin)^# Nutropin (somatropin)^# PREFERRED Nutropin AQ (somatropin)^# PREFERRED Omnitrope (somatropin)^# Saizen (somatropin)^# Serostim (somatropin)^# Signifor (pasireotide)^# Tev-tropin (somatropin)^# Zorbtive (somatropin)^#
Miscellaneous Endocrine Disorders
H.P. Acthar gel (corticotrophin)^ Korlym (mifepristone)^ Procysbi (cysteamine bitartrate)^ Ravicti (glycerol phenylbutyrate)^ Sandostatin LAR Depot (octreotide acetate) Somatuline Depot (lanreotide acetate) Somavert (pegvisomant) Supprelin LA (histrelin acetate) Osteoporosis Boniva IV formulation only (ibandronate)^ Forteo (teriparatide)^ Prolia (denosumab)^ zoledronic acid^ Phenylketonuria Treatment Agents Kuvan GASTROENTEROLOGY Crohns, UC
Cimzia (certolizumab)^# Humira (adalimumab)^# PREFERRED self administered Remicade (infliximab)^ PREFERRED provider administered Tysabri (natalizumab)^ HEMATOLOGICAL Anemia
Aranesp (darbepoetin alfa)^ Epogen (epoetin alfa)^ Procrit (epoetin alfa)^ PREFERRED
Fibrinogen Deficiency Hemophilia Hemophilia, Factor IX Alphanine
Bebulin Benefix Mononine Profilnine SD Proplex T
Hemophilia, Factor VIIa Novoseven
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter P = Preferred drug; N = Non-Preferred Drug UPPERCASE = BRAND; lowercase = generic ^=May require Prior Authorization for some plans PREFERRED - These medications are preferred within their class. NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
Hemophilia, Factor VIII
Helixate FS Hemofil M Humate-P Koate-DVI Kogenate FS Monoclate-P Recombinate Refacto Wilate (VWF/FactorVIII) XynthaHereditary Angioedema
Berinert (C1 esterase inhibitor)^# Cinryze (human C1 inhibitor)^# Firazyr (icatibant)^#
Immune Globulins Carimmune^ Flebogamma^ Gamastan^ Gammagard^ Gamunex^ PREFERRED, Gamunex-C^ PREFERRED Hizentra^ Octagam^ Privigen^ Vivaglobin^ Miscellaneous Mozobil (plerixafor) Thrombocytopenia WBC Deficiencies
Leukine (sargramostim) Neulasta (pegfilgrastim)# Neupogen (filgrastim)
IMMUNOMODULATOR Cryopyrin-Associated Periodic Syndromes Arcalyst Lupus Erythematosus Benlysta (belimumab)^ Rheumatoid Arthritis Actemra (tocilizumab)^# Cimzia (certolizumab)^# Enbrel (etanercept)^# PREFERRED self administered Humira (adalimumab)^# PREFERRED self administered Kineret (anakinra)^ Orencia (abatacept)^# Remicade (infliximab)^ PREFERRED provider administered Rituxan (rituximab)^ Simponi (golimumab)^ Xekljanz (tofacitinib)^# IMMUNOSUPPRESSIVE Transplant Drugs INFERTILITY Follitropins
Follistim AQ (follitropin beta) PREFERRED Gonal-F (follitropin alfa)
GnRH Antagonists
Cetrotide (cetrorelix acetate) Ganirelix acetate
chorionic gonadotropin (generic) Novarel (chorionic gonadotropins) Ovidrel (choriogonadotropin alfa) Pregnyl (chorionic gonadotropins)
Menotropins
Menopur (gonadotropins/menotropins) Repronex (gonadotropins/menotropins)
Urofollitropins MISCELLANEOUS Neurologicals Chronic Gout Krystexxa (pegloticase)^
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter P = Preferred drug; N = Non-Preferred Drug UPPERCASE = BRAND; lowercase = generic ^=May require Prior Authorization for some plans PREFERRED - These medications are preferred within their class. NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
Enzyme Replacements Aldurazyme (laronidase) Carbaglu (carglumic acid)^ Cerezyme (imiglucerase) Elaprase (idursulfase) Elylyso (paliglucerase alfa)^ Fabrazyme (agalsidase beta) Lumizyme (alglucosidase alfa)^ Myozyme (alglucosidase alfa)^ Naglazyme (galsulfase) Vpriv (velaglucerase)^ Zavesca (miglustat)^ Iron Overload
Exjade (deferasirox)^ Ferriprox (deferiprone)^
Macular Degeneration Eylea (aflibercept)^# Lucentis (ranibizumab)^ Macugen (pegaptanib)^ NEUROMUSCULAR Huntington's Multiple Sclerosis
Ampyra (dalfampridine)^ Aubagio (teriflunomide)^ Avonex (interferon beta 1a) Betaseron (interferon beta 1b) Copaxone (glatiramer) Extavia (interferon beta 1b) Gilenya (fingolimod)^ Rebif (interferon beta 1a) Tecfidera (dimethyl fumartae)^# Tysabri (natalizumab)^ Muscular Disorder Botox (botulinum toxin type A)^ Dysport (botulinum toxin type A)^ Myobloc (botulinum toxin type B)^ Xeomin (botulinum toxin type A)^ ONCOLOGY/HEMATOLOGY Hematology NPlate (romiplostim)^ Promacta (eltrombopag olamine)^ Oral Agents
Afinitor (everolimus)^ Bosulif (bosutinib)^ Caprelsa (vandetanib)^# Cometriq (cabozantinib)^ Erivedge (vismodegib)^# Gleevec (imatinib)^ Iclusig (ponatinib)^ Inlyta (axitinib)^ Iressa (gefitinib) Jakafi (ruxolitinib)^ Mekinist (trametinib)^ Nexavar (sorafenib)^ Oforta (fludarabine)^ Pomalyst (pomalidomide)^# Revlimid (lenalidomide)^# Sprycel (dasatinib)^ Stivarga (regorafenib)^ Sutent (sunitinib)^ Tafinlar (dabrafenib)^ Tarceva (erlotinib)^ Targretin caps (bexarotene)^ Tasigna (nilotinib)^ Temodar (temozolomide)^ Thalomid (thalidomide)^ Tykerb (lapatinib)^ Votrient (pazopanib)^ Xalkori (crizotinib)^# Xeloda (capecitabine)^ Xtandi (enzalutamide)^# Zelboraf (vemurafenib)^# Zolinza (vorinostat)^
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter P = Preferred drug; N = Non-Preferred Drug UPPERCASE = BRAND; lowercase = generic ^=May require Prior Authorization for some plans PREFERRED - These medications are preferred within their class. NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
Topical Agents Injectable Agents Eligard (leuprolide acetate) PREFERRED Firmagon (degarelix) Lupron Depot (leuprolide acetate)^ Sylatron (peginterferon alfa-2b)^ Trelstar Depot (triptorelin pamoate) Trelstar LA (triptorelin pamoate) Vantas (histrelin acetate) Xgeva (denosumab)^ Zoladex (goserelin acetate) PULMONARY Asthma Xolair (omalizumab)^ Cystic Fibrosis
Cayston (aztreonam inhaled) Kalydeco (ivacaftor)^# Pulmozyme (dornase alfa inhaled) TOBI (tobramycin inhaled)
Pulmonary Hypertension epoprostenol^
Adcirca (tadalafil)^# Flolan (epoprostenol)^ Letairis (ambrisentan)^# Remodulin (treprostinil)^ Revatio (sildenafil)^# Tracleer (bosentan)^# Tyvaso (treprostinil)^ Ventavis (iloprost inhaled)^
Respiratory Enzymes Aralast (alpha1 proteinase inhibitor) Glassia (alpha1 proteinase inhibitor) Prolastin (alpha1 proteinase inhibitor) Zemaira (alpha1 proteinase inhibitor) Synagis (palivizumab)^ Preferred Specialty Vendors VILLAGE FERTILITY PHARMACY CAREMARK CONNECT Resource Information for Physicians/Providers BLUE CROSS & BLUE SHIELD OF RHODE ISLAND
Local (401) 459-1000 • Toll free 1-800-637-3718
PATIENT HEALTH EDUCATION PROGRAMS PHYSICIAN AND PROVIDER SERVICE
We reserve the right to make changes to this list. Upon availability of generic equivalents, Brand drug coverage status may change without written notice. Please refer to our website @
www.bcbsri.com for the most current information. Questions? Please call the Customer Service number on the back of your ID card.
# - Quantity Limits for some plans; * = tier 2 generic OTC - Over the Counter P = Preferred drug; N = Non-Preferred Drug UPPERCASE = BRAND; lowercase = generic ^=May require Prior Authorization for some plans PREFERRED - These medications are preferred within their class. NC = Not Covered - Drugs not covered are not eligible for an exception process. NCE = Not Covered, eligible for medical criteria exception This drug list represents a summary of prescription coverage. It is not inclusive and does not guarantee coverage.
Adverse Oral and Dental Effects of Medications Case Western Reserve University School of Medicine Associate Clinical Professor of Pharmacy Practice * The author wishes to thank and acknowledge Wendy Gesaman and Sandy Discuss the various categories of adverse dental and oral effects of Provide specific examples of drugs that are associated with corresponding Describe the mechanisms by which d
Reproduced from Asian Agri-History Vol. 8, No. 2, 2004 (115–127) On Elephants in Manasollasa – 2. Diseases and Treatment Nalini Sadhale1 and Y L Nene2 1. B-1, Kanakalaxmi Apartments, Street No. 6, Hardikar Bagh, Himayatnagar, Hyderabad – 500 029, Andhra Pradesh, India (email: nalinisadhale@vsnl.net) 2. Asian Agri-History Foundation, Secunderabad – 500 009, Andhra Pradesh, India