2519 doxycycline, hydrochloride (english) msds north america/ansi z400.1/dynamic/v. 3.

Material Safety Data Sheet
Order Number
Customer
Number
Section 1. Chemical Product and Company Identification
Common Name
Doxycycline, Hydrochloride
Catalog #
Supplier
In Case of
Call Chemtrec®
Emergency
(800)424-9300 (within U.S.A.)
(703)527-3887 (outside U.S.A.)
(858)450-5558/(800)854-3417FAX: (858)453-3552 D O X Y C Y C L I N E , H Y D R O C H L O R I D E ; B I O C A M Y C I N ;DOXIGALUMICINA; DOXYCYCLINE HYCLATE; DOXY-II;DOXY-TABLINEN; ECODOX; HYDRAMYCIN; LIOMYCIN;MESPAFIN; MIDOXIN; NIVOCILIN; NOVADOX; RETENS;ROXIMYCIN; SAMECIN; TANAMICIN; TECACIN; TETRADOX;VIBRADOX; VIBRAMYCIN HYCLAT E; VIBRA-TABS Section 2. Composition, Information on Ingredients
Exposure Limits
Section 3. Hazards Identification
Physical State and
Appearance
Emergency Overview
MAY BE HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
MAY CAUSE BIRTH DEFECTS BASED ON ANIMAL DATA.
Avoid prolonged contact with eyes, skin, and clothing. Do not ingest. Avoid breathing dust. Keep containerclosed. Use only with adequate ventilation. Avoid exposure during pregnancy. Wash thoroughly afterhandling.
Routes of Entry
Absorbed through skin. Dermal contact. Inhalation. Ingestion.
Potential Acute Health Effects
Eyes Not available.
Skin Hazardous in case of skin contact (permeator).
Inhalation Hazardous in case of inhalation.
Ingestion Hazardous in case of ingestion.
Potential Chronic Health
CARCINOGENIC EFFECTS : Classified None. by NIOSH.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Classified POSSIBLE for human.
Medical Conditions
Repeated exposure to a highly toxic material may produce general deterioration of health by an accumulation Aggravated by Overexposure: in one or many human organs.
Overexposure
/Signs/Symptoms
See Toxicological Information (section 11)
Catalog #
Page: 1/5
Section 4. First Aid Measures
Eye Contact
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water forat least 15 minutes. Cold water may be used. Get medical attention.
Skin Contact
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes.
Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medicalattention.
Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Ingestion
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to anunconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosentight clothing such as a collar, tie, belt or waistband.
Notes to Physician
Section 5. Fire Fighting Measures
Flammability of the Product
May be combustible at high temperature.
Flash Points
Products of Combustion
These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.), halogenated compounds.
Fire Hazards in Presence of
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
of Various Substances
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media
SMALL FIRE: Use DRY chemical powder.
and Instructions
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Protective Clothing (Fire)
Be sure to use an approved/certified respirator or equivalent.
Special Remarks on Fire
Special Remarks on Explosion Not available.
Hazards
Section 6. Accidental Release Measures
Small Spill and Leak
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning byspreading water on the contaminated surface and dispose of according to local and regional authorityrequirements.
Large Spill and Leak
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreadingwater on the contaminated surface and allow to evacuate through the sanitary system.
Section 7. Handling and Storage
Handling
Avoid prolonged contact with eyes, skin, and clothing. Do not ingest. Avoid breathing dust. Keep containerclosed. Use only with adequate ventilation. Wash thoroughly after handling.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 4°C(39.2°F).
Catalog #
Page: 2/5
Section 8. Exposure Controls, Personal Protection
Engineering Controls
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels belowrecommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keepexposure to airborne contaminants below the exposure limit.
Personal Protection
Eyes Safety glasses.
Body Lab coat.
Respiratory Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Hands Gloves.
Feet Not applicable.
Protective Clothing
(Pictograms)
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be
a Large Spill
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult aspecialist BEFORE handling this product.
Product Name
Exposure Limits
Consult local authorities for acceptable exposure limits.
Section 9. Physical and Chemical Properties
Physical State and
Appearance
Molecular Weight
Molecular Formula
Boiling/Condensation Point
Melting/Freezing Point
Specific Gravity
Vapor Pressure
Vapor Density
Solubility
Section 10. Stability and Reactivity
Stability and Reactivity
Incompatibility with Various
Substances
Hazardous Decomposition
These products are halogenated compounds.
Products
Hazardous Polymerization
Catalog #
Page: 3/5
Section 11. Toxicological Information
QI8925000
Toxicity to Animals
Acute oral toxicity (LD50): >500 mg/kg [Dog].
Chronic Effects on Humans
CARCINOGENIC EFFECTS : Classified None. by NIOSH.
TERATOGENIC EFFECTS: Classified POSSIBLE for human.
Other Toxic Effects on
Hazardous in case of skin contact (permeator), of ingestion, of inhalation.
Special Remarks on Toxicity to Not available.
Animals
Special Remarks on Chronic
May cause congenital malformations in the foetus.
Effects on Humans
Special Remarks on Other
Toxic Effects on Humans
Section 12. Ecological Information
Ecotoxicity
Toxicity of the Products of
The products of degradation are less toxic than the product itself.
Biodegradation
Section 13. Disposal Considerations
Waste Information
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Waste Stream
Consult your local or regional authorities.
Section 14. Transport Information
DOT Classification
Not a DOT controlled material (United States).
TDG Classification
Marine Pollutant
Special Provisions for
Transport
ADR/RID Classification
IMO/IMDG Classification
ICAO/IATA Classification
Catalog #
Page: 4/5
Section 15. Regulatory Information
HCS Classification
Not controlled under the HCS (United States).
U.S. Federal Regulations
TSCA: No products were found.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: Doxycycline, HydrochlorideSARA 311/312 MSDS distribution - chemical inventory - hazard identification: Doxycycline, Hydrochloride:delayed health hazardSARA 313 toxic chemical notification and release reporting: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
WHMIS (Canada)
Not controlled under WHMIS (Canada).
International Regulations
DSCL (EEC)
R20/21/22- Harmful by inhalation, in contact with skin and if swallowed.
R63- Possible risk of harm to the unborn child.
International Lists
Australia (NICNAS): Doxycycline, Hydrochloride State Regulations
California prop. 65: This product contains the following ingredients for which the State of California has foundto cause birth defects which would require a warning under the statute: Doxycycline, Hydrochloride Section 16. Other Information
Label Requirements
MAY BE HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
MAY CAUSE BIRTH DEFECTS BASED ON ANIMAL DATA.
Hazardous Material
National Fire
Fire Hazard
Information System
Fire Hazard
1 Protection Association
(U.S.A.)
(U.S.A.)
Reactivity
0 Reactivity
Personal Protection
Specific Hazard
Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries
assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used
with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.
Date of issue
Catalog #
Page: 5/5
11/8/2001.

Source: http://www.setonresourcecenter.com/msdshazcom/htdocs//MSDS/E/EMD/Docs/wcd00008/wcd00825.pdf