Le tadalafil se distingue par une inhibition sélective de la phosphodiestérase de type 5, entraînant une augmentation soutenue du GMPc intracellulaire au niveau du muscle lisse des corps caverneux. Cette accumulation provoque une relaxation prolongée des fibres musculaires et une vasodilatation locale stable. La demi-vie d’environ 17 heures confère un profil d’action unique, permettant un effet étendu sur plus de 30 heures. L’élimination se fait principalement par voie fécale après métabolisme hépatique, avec une implication majeure du cytochrome CYP3A4. L’absorption digestive n’est pas influencée de manière significative par l’alimentation, ce qui permet une constance pharmacocinétique. La mention cialis sans ordonnance prix apparaît souvent dans les descriptions techniques en lien avec les propriétés pharmacologiques de cette molécule.

Microsoft powerpoint - guijarro, elena, understanding schizophrenia short version najit

• A serious, chronic and disabling brain disorder characterized by profound disruption in cognition, emotion, affecting the most fundamental human attributes: language, thought, perception, affect and sense of self.
• It affects 1% of the population • It attacks people between the ages of 15 and 30 • (Surgeon General, 2009, Adults and Mental • Positive symptoms:
• hal ucinations: visual, auditory,
• (National Institute of Mental Health • Negative symptoms:
• alogia
• flat or blunted affect
• avolition
• anhedonia
• (NIMH, 2009, Schizophrenia, para. 13) • Disorganized symptoms:
• thought disorder
• grossly disorganized behavior
• catatonic behavior
• (NIMH, 2009, Schizophrenia, para. 13) Cognitive symptoms:
difficulty integrating thoughts, feelings and (Surgeon General, 2009, Adults and Mental Health, • Paranoid schizophrenia• Disorganized schizophrenia (Hebephrenic • Catatonic schizophrenia• Residual schizophrenia• Undifferentiated Schizophrenia • (American Psychiatric Association, 2000. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition with ≥ 2 characteristic symptoms for a • Antipsychotic drugs• Rehabilitation, including community • (The Merck Manuals Online, Treatment, 2008, • Flupenthixol (Fluanxol) • Loxapine (Loxapac, Loxitane) • Perphenazine (Etrafon, Trilafon) • Chlorpromazine (Thorazine) • Haldol ( Haloperidol) • Prolixin (Fluphenazine Decanoate, Modecate, • (Mayo Clinic Staff, Treatment and Drugs, 2008, • Abilify (Aripiprazole)• Clozaril, Denzapine, Zaponex (clozapine) • Geodon (Ziprasidone) • Risperdal (Risperidone) • Seroquel (Quetiapine) • Zyprexa (Olanzapine) • Invega (Paliperidone) • (Mayo Clinic Staff, Treatment and Drugs, 2008, para. 6) • Age at onset• Functioning level prior to the onset of • Cognitive impairment• Type of symptoms (positive vs. negative)• Family history of mental illness • Treatment compliance • Biological • Neurodevelopmental vulnerability• Environmental stressors • Schizophrenia is a split personality • People with schizophrenia are violent • The family causes schizophrenia • There is no hope of people with • (Recover.ie, 2009, Myths and Facts, para. 2 ) • Schizophrenia is a split from reality rather • People with schizophrenia are not more violent than any other group in society.
• Schizophrenia is not caused by the family• People do improve and recover and hope is regarded as an essential ingredient for • (Recover.ie, 2009, Myths and Facts, para. 2 ) • DON'T THREATEN-This may be interpreted as a power play and increase fear or prompt assaultive behavior. • DON'T SHOUT-If the person isn't listening, other "voices" are probably interfering. • DON'T CRITICIZE-It will make matters worse; it can't • DON'T SQUABBLE WITH OTHER FAMILY MEMBERS over "best strategies" or allocations of blame. This is no • DON'T BAIT THE PATIENT-Into acting out wild threats; • DON'T STAND OVER THE PATIENT-If he is endangering or beyond reason. This gives the patient the opportunity to feel somewhat "In yourself between the patient and an exit.
• (Schizophrenia.com., 2008, Tips, para. 6).
• American Psychiatric Association. (2005).
Schizophrenia. Diagnostic and Statistical Manual of Mental Disorders (4th ed. text revision, pp. 298 – • Mayo Clinic Staff. (2008). Treatments and drugs. In Basics: Schizophrenia. Mayoclinic.com. Retrieved http://www.mayoclinic.com/health/schizophrenia/DS • National Institute of Mental Health (NIMH). (2009).
Schizophrenia. In Mental Health Topics. National Institute of Mental Health (NIMH). Retrieved on http://www.nimh.nih.gov/health/topics/schizophrenia/ • Recover.ie. (2009). Myths and Facts. In What is Schizophrenia? Recover.ie. Retrieved on March 29, http://www.recover.ie/info.php?to_one=1&to_two=29 • Schizophrenia.com. (2008). Schizophrenia Symptoms. In Information on Schizophrenia. Schizophrenia.com. Retrieved on March 13, 2009 from http://www.schizophrenia.com/diag.php Schizophrenia. In Schizophrenia and Related Disorders. The Merck Manuals Online Medical Library. Retrieved on March 27, • U.S. Public Health Service. (2009). Report of the Surgeon General on Adults and Mental Health: Schizophrenia. Washington, DC: U.S. Department of Health and Human Services. Retrieved on March 10, 2009 from http://www.surgeongeneral.gov/library/menta

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