Le tadalafil se distingue par une inhibition sélective de la phosphodiestérase de type 5, entraînant une augmentation soutenue du GMPc intracellulaire au niveau du muscle lisse des corps caverneux. Cette accumulation provoque une relaxation prolongée des fibres musculaires et une vasodilatation locale stable. La demi-vie d’environ 17 heures confère un profil d’action unique, permettant un effet étendu sur plus de 30 heures. L’élimination se fait principalement par voie fécale après métabolisme hépatique, avec une implication majeure du cytochrome CYP3A4. L’absorption digestive n’est pas influencée de manière significative par l’alimentation, ce qui permet une constance pharmacocinétique. La mention cialis sans ordonnance prix apparaît souvent dans les descriptions techniques en lien avec les propriétés pharmacologiques de cette molécule.

Digital_cv2004

RESUME 3D Artist/Modeler - Designer
[ PROFESSIONAL SUMMARY ]
Skilled, experienced and versatile 3D professional with nearly 20 years of combined experience using digital and traditional media. Worked as a staff artist and as an independent designer. Extensive background in the digital/traditional arts including character design, toy and product design, cutting edge medical animation and web based solutions. Self motivated, innovative, adapts quickly to new solutions and works well under pressure - meeting all challenging and mission critical deadlines. Obsessed with creative challenges beckoning 3d solutions. Seeks professional and freelance opportunities in 3D design. [ PROFESSIONAL AREAS OF EXPERTISE ]
• Digital and traditional 3D character and prop modeling • Photorealistic texturing & rendering • Digital and traditional pattern development • Human and “un-human” anatomical expert • Character modeling, maquettes & style guides • Mock ups • 2D Illus-tration & Design • Maya • Lightwave 3D • Electric Image Universe • Painter3D • Photoshop • Illustrator • QuarkXpress • InDesign • After Effects • Final Cut Express • MS Word/Office • Golive 6 • Red Hat Linux • MAC OSX 10.3, MAC OS 9.2.2 and Windows 2000/XP [ CAREER HIGHLIGHTS ]
• I, Robot - Modeled and developed the design of the NS5 robot under Patrick Tatopoulis using Maya and Lightwave 3D
• Star Wars Trilogy - Created the Star Wars Trilogy movie poster to represent the latter three films for Lucas Film.
• Digital Hero Award - Designed, developed and manufactured the Digital Hero for 3D Festival, Sweden.
• Merck Medicus - Conceptualized, designed and developed the Merck Medicus 3D icon.
• Terminator 2 - Created a motion controlled puppet of Arnold Schwarzeneggar in “T2” – the special effects received an
Academy Award
• Digital Hall of Fame - Distinguished member and recipient
• Merck - Listed as a “Merck Preferred Vendor” for 3D medical animation, 3D illustration and educational products
[ DIGITAL 3D WORK HISTORY ]
MEDICAL: Designed & manufactured medical 3D models, animations & visuals for Merck & Co, Inc., Abbot Labs,

Corbett Healthcare, National Comprehensive Cancer Network • CD4 Cell physician/patient model • Singulair physician/patient lung model • Crixivan medical poster • Medicus logo • Crixivan HIV mechanism of action booklet and slide series • HIV level of potency animation • Medicus intro animation• Promotional Medicus key chain • Promotional Medicus ergo computer mouse • CD4 Cell model box art GAME ANIMATICS & MODELS: Created and designed digital/traditional models for the Arcade and Game industry
• Vivendi Universal: 3D box art illustration for Dark Ages of Camelot, DAoC Gold Edition, Predator (2002 to 2004)• Blizzard Entertainment: Action figure character design, creation and manufacturing (1999 - 2002)• vTorque: Character modeling for MotoXXX, Lu Vampyr game animatics (2002 to 2004)• Atari Games: Character design and model construction for Primal Rage and Area 51 (1993 - 1995) 3D Misc: Various, recent digital modeling projects (2003 - 2004)
• Lightsport™ (product modeling) • Somerset Ent. (anatomical modeling for box art) • Master Replicas (product modeling) • Asylum (box art) • Mattel (Action figures and accessories) Relevant “Analog & Digital” 3D work history continued. [ FILM ACCOMPLISHMENTS - 1989/2004] Digital modeling, miniatures, puppets, make-up effects, design and fabrication
• A Day with Wilbur Robinson (in Production) • Curandero (in Production) • The Cave • I, Robot • Gnomeo & Juliet • The Addams Family • Area 51 • Army of Darkness • Batman Returns • Dark Warrior • Dinosaur City • Ernest Scared Stupid • Escape from LA • Exorcist III • Freakz • Gremlins 2 • Honey, I blew up the baby • Hall of Energy – Epcot Astronaut • Harley Davidson and Marlboro Man • Highlander 2 • Hook • Innocent Blood • Jurassic Park • Kick Boxer 2 • Leeds Point • Nemesis • Pet Semetary 2 • Primal Rage • Star Wars Trilogy – Movie poster • Terminator 2 • Ticks • True Lies • Warlock [ TV ACCOMPLISHMENTS - 1989/1996 ] Miniature puppet effects, make-up effects, design and fabrication
• Alice in Wonderland • Andersonville • …and the sea will tell • Attack of the 50 foot women • The Beast • Christmas at Target – Ginger Bread dancers commercial • Coast Soap “The Thinker” commercial • Danger Island • Deep Space 9 • Hunchback of Notre Dame • IT • John Lee Hooker video • Land of the Lost • MGM Grand International restaurants commercial • Monsters - Manikins of Horror • Playboy Centerfold video • Shake, Rattle & Roll • Tru – The play [ TOY ACCOMPLISHMENTS -1990/2003 ] Designed, developed and manufactured action figures, dolls & models
• Alien Resurrection • Battle Squads • Bela Lugosi doll • Bernie Wrightson’s Frankenstein • C3PO • Diablo 2 • The Flintstones • Classic Disney • Gargoyles • Godzilla • Hercules • The Jersey Devil • Judge Dredd • Jurassic Park Chaos • Major League Baseball • National Football League • NYFD 9/11 Memorial firefighter doll • Orcaphant • The Phantom • Planet of the Apes • Rocky and Bullwinkle • Samaritan doll • Savage Dragon • Schlitzie and Lionel • Shaft • Small Soldiers • Spawn • Street Sharks • Star Craft • Starship Troopers • Star Trek - Nemesis • Stryker • Violator • Visitor • Warcraft • Warcraft 3 [ WRITER / LECTURER ]
Topic range: Digital 3D modeling, 3D design & manufacturing • Featured speaker, Disney Feature Animation “One of our own series - (Burbank, CA - 2005)• Guest speaker on Maya character development at Cal Arts - 2005• Guest speaker, 3D Festival/LEAF (London - 2002) • Art of 3D computer animation and imaging book - (Contributing artist, 2002)• 2 day guest speaker/demo artist at Denver University, 2002• Guest speaker, panelist and demo artist at the 3D Festival (Denmark and Sweden - 1999/2001) • Guest speaker at Siggraph 2001, Newtek booth• Guest panelist at the 3D Expo 2000• 3D Demo artist at MacWorld - 2000 • Guest speaker at Art Center, 1999 • EFX Art and Design Magazine (Associate Editor - 1998/2002) • Mastering Pixels 3D book (Contributing writer, 2000) • Pixels 3D Power User Tutorials (Co-author, 2000)• Amazing Figure Modeler Magazine (Columnist, 1994/1996) [ EDUCATION ]
• B.F.A. Major: Illustration, Minor: Sculpture, Philadelphia University of the Arts, 1987 • Received “Exceptional calibre” (highest level) in Special Makeup Effects Artistry in the Motion Picture Industry, 1988 5134 Oakdale Ave . Woodland Hills, C A 91364 Tel. 818-887-2585 dan@solidimagear ts.com

Source: http://www.solidimagearts.com/digital_freelance_CV.pdf