Site brasileiro onde você pode comprar qualidade e entrega viagra preço cialis barato em todo o mundo.

Microsoft word - trust formulary (revised 2013) - 10 2013 update

DRUG FORMULARY

Updated after HEY Drug and Therapeutics Committee meeting Of September 2013

This formulary is used and maintained by Hull and East Yorkshire Hospitals NHS Trust.

It is also used as a formulary by Humber Foundation NHS Trust (HFT) and City Health
Care Partnership (CHCP).

The formulary has been agreed with Hull Clinical Commissioning Group and East Riding
of Yorkshire Clinical Commissioning Group
with the expectation that providers within Hull
and East Riding will prescribe and recommend drug treatments from those listed in the
formulary.
A joint formulary is currently in development

Guide:

Bold and highlighted = preferred first line agent
Italics = specialist recommendation only Other agents = can still be used, but are not preferred first line agent
Drugs not listed are considered non formulary, and will not be supplied from hospital
pharmacy. Non formulary drugs should not be recommended for initiation in primary
care.
For further information on formulary process, including application for use of
additional agents within individual organisations, see contact details below:

Hull and East Yorkshire Hospitals NHS Trust
Simon Gaines, Senior Principal Pharmacist – Clinical Services Tel. 01482 675587, e-mail Simon.Gaines@hey.nhs.uk Weeliat Chong, Chief Pharmacist Tel. 01482 301727, e-mail Weeliat.Chong@humber.nhs.uk Graham Hill / Emma Baggaley, Senior Pharmacist Tel. 01482 344151, e-mail Graham.Hill1@chcphull.nhs.uk, Emma.Baggaley@chcphull.nhs.uk Jackie Lyon, Head of Medicines Management, York & Humber CSU Tel. 0148 672029, email jackie.lyon@nhs.net Marie Miller, Senior Principal Pharmacist – Interface, HEY Tel. 01482 675207 or 674731, e-mail marie.miller@hey.nhs.uk Emergency Treatment of Poisoning

Charcoal, activated
Acetylcysteine
Methionine
Dehydrated (absolute) alcohol/ethanol
Other agents are listed elsewhere in the formulary.

CHAPTER 1: GASTRO-INTESTINAL DRUGS
1.1 ANTACIDS
Sodium

1.1.1 Aluminium and Magnesium containing
Magnesium Trisilicate
Aluminium Hydroxide
Maalox®
Mucaine®
Simeticone Infacol®

1.1.2 Sodium Bicarbonate
Sodium Bicarbonate
1.1.3 Other drugs for dyspepsia and GORD.
Gaviscon Advance®
Gaviscon Infant®
1.2 ANTISPASMODICS
ANTIMUSCARINICS
Hyoscine butylbromide
Alverine Citrate
Propantheline
Peppermint water
MOTILITY STIMULANTS
Metoclopramide/Domperidone - see 4.6
1.3 ULCER HEALING DRUGS
1.3.1 H2 receptor antagonists
Ranitidine


1.3.3 Chelates and Complexes


1.3.5 Proton pump inhibitors

Lansoprazole
Omeprazole (Oral ONLY)
Pantoprazole (Intravenous ONLY)
Esomeprazole

1.4 ANTIDIARRHOEAL DRUGS
1.4.2 Antimotility drugs
Loperamide

NOT for under 12 years old or breastfeeding mothers


1.5 TREATMENT OF CHRONIC DIARRHOEA
AMINOSALICYLATES
Mesalazine
* Remember to clarify the brand of SR products *
CORTICOSTEROIDS Hydrocortisone 10% foam Hydrocortisone suppository Prednisolone enemas and suppository Budesonide
1.6 LAXATIVES
1.6.1 Bulk forming
Fybogel

1.6.2 Stimulant
Senna

Docusate Sodium Glycerin Suppositories Adult, Children Sodium Picosulfate Co-danthramer
1.6.3 Faecal Softeners
Arachis Oil retention enemas
1.6.4 Osmotic
Phosphate enemas
Relaxit enemas Magnesium Sulphate Macrogol sachets (e.g. Laxido®, Movicol®) Movicol Liquid Lactulose solution
1.6.5 Bowel Cleansing Solutions
Fleet-Phospho Soda® oral solution
Picolax

1.6.6 Peripheral Opioid-receptor Antagonists
Methylnaltrexone bromide injection

1.6.7 5HT4 receptor agonists
Prucalopride (for women, in line with NICE TA211)
Linaclotide
1.7 PREPARATIONS FOR ANAL AND RECTAL DISORDERS
Anal fissures
Glyceryl trinitrate ointment 0.4% (Rectogesic)

Diltiazem ointment 2%


1.7.1 Soothing
Anusol

1.7.2 Compound

Proctosedyl
1.7.3 Rectal Sclerosants
Oily Phenol Injection
1.9 DRUGS AFFECTING INTESTINAL SECRETIONS
1.9.1 Drugs acting on Gall Bladder
Ursodeoxycholic

1.9.4 Pancreatin
Creon
CHAPTER 2: CARDIOVASCULAR SYSTEM

2.1 POSITIVE INOTROPIC DRUGS
2.1.1 Cardiac Glycosides
Digoxin


2.1.2 Phosphodiesterase Inhibitor
Enoximone

2.2 DIURETICS
2.2.1 Thiazides and Related

Bendroflumethiazide (Bendrofluazide)
Indapamide
Indapamide SR

Metolazone

2.2.2 Loop
Furosemide (Frusemide)
Bumetanide

2.2.3 Potassium sparing
Amiloride
2.2.4 Potassium sparing with other Diuretics
Co-amilofruse
For other combinations - use separate formulary agents

2.2.5 Osmotic
Mannitol

2.2.7 Carbonic Anhydrase Inhibitors
Acetazolamide

2.3 ANTI ARRHYTHMIC DRUGS
2.3.2 Drugs for arrhythmias
SUPRAVENTRICULAR
Adenosine injection
VENTRICULAR
Amiodarone
Sotalol
Lidocaine (Lignocaine) in Dextrose infusion Mexiletine
2.4 BETA-ADRENOCEPTOR BLOCKING DRUGS

Timolol
Bisoprolol Esmolol Cardiology/Theatres Labetalol 2.5.2 Centrally acting
Clonidine
Methyldopa

Moxonidine

2.5 ANTIHYPERTENSIVE AGENTS
2.5.1 Vasodilator
Diazoxide
Hydralazine


2.5.4 Alpha blockers
Doxazosin

PHAEOCHROMOCYTOMA
Phenoxybenzamine

Phentolamine injection

2.5.5.1 ACE inhibitors

Lisinopril
Captopril
2.5.5.2 Angiotensin II receptor antagonists
Valsartan
Candesartan
Losartan
2.5.5.3 Renin Inhibitor
Aliskiren

2.6 VASODILATORS
2.6.1 Nitrates
Glyceryl Trinitrate

Isosorbide Mononitrate
Isosorbide Dinitrate injection

2.6.2 Calcium channel blockers
Please specify the brand of agent and strength used if SR/LA.
Amlodipine

For continuation of GP initiated treatment
2.6.3 Potassium channel activators
Nicorandil
Ivabradine

2.6.4 Peripheral vasodilators
Naftidrofuryl

2.7 SYMPATHOMIMETICS
2.7.1 Inotropic sympathomimetics
Dobutamine

2.7.2 Vasoconstrictor sympathomimetics
Adrenaline
Phenylephrine Injection
Ephedrine Injection

2.8 ANTICOAGULANTS
2.8.1 Parenteral anticoagulants

LOW MOLECULAR WEIGHT HEPARINS
Dalteparin
treatment,
DVT treatment and prophylaxis
Bivalirudin Epoprostenol Lepirudin
2.8.2 Oral anticoagulants
Warfarin
Acenocoumarol
Dabigatran Orthopaedics / Cardiology/Stroke Physicians Rivaroxaban Available on chairs approvals for patients meeting NICE TA 245, TA275 who are unable to have the trust preferred options
2.8.3 Protamine sulphate
Protamine sulphate

2.9 ANTIPLATELET DRUGS
Aspirin


Abciximab

2.10.2 FIBRINOLYTIC DRUGS
Alteplase


2.11 ANTIFIBRINOLYTIC DRUGS AND HAEMOSTATIC AGENTS
Tranexamic Acid

BLOOD PRODUCTS
Haematology Department
2.12 LIPID LOWERING DRUGS.
ANION EXCHANGE
Colestyramine
Gemfibrozil Bezafibrate SR as Bezalip® Mono FISH OILS Omega-3-acid ethyl esters (Omacor®) Lipid Specialist & Continuation of treatment only Ezetimibe

2.13 LOCAL SCLEROSANTS
Ethanolamine
Polidocanol (Scleroven)® Surgery CHAPTER 3: RESPIRATORY SYSTEM

3.1 BRONCHODILATORS
3.1.1.1 Selective 2 Adrenoreceptor Stimulants
Short acting
Salbutamol


Long acting
Salmeterol
Formoterol
Indacaterol


3.1.1.2 Other Adrenoreceptor stimulants
Adrenaline aerosol (Primatene Mist®)
3.1.2 Antimuscarinic bronchodilators

Ipratropium
Tiotropium

3.1.3 Theophylline
* Remember to clarify the brand of SR products *
Aminophylline
Theophylline

3.1.4 Compound Bronchodilator Preparations
Combivent

3.2 CORTICOSTEROIDS
Beclometasone (Beclomethasone)

Clenil Modulite® (First line in children) Prescribe by brand
Qvar® (First line in adults) Prescribe by brand

Flutiform® Respiratory Specialist
3.3 CROMOGLICATE AND RELATED THERAPY
Nedocromil
Sodium Cromoglicate(Sodium Cromoglycate) Respiratory Specialist 3.3.2 Leukotriene receptor antagonists
Montelukast

PHOSPHODIESTERASE TYPE 4 INHIBITORS
3.3.3
Roflumilast Respiratory medicine for existing patients only in line with NICE TA244

3.4 ANTIHISTAMINES AND RELATED THERAPY
3.4.1 Antihistamines
NON-SEDATING ANTIHISTAMINES
Cetirizine
Fexofenadine
SEDATING ANTIHISTAMINES
Chlorphenamine (Chlorpheniramine)
Hydroxyzine Promethazine Alimemazine (Trimeprazine)
3.4.2 Allergen Immunotherapy
Omalizumab
(Not recommended in children aged 6 to 11 years as per NICE TA201) Grass and tree pollen extracts - Grazax®
3.4.3 Allergic emergencies
Adrenaline
Epipen
Icatibant Immunology

C1 Esterase Inhibitor (Berinert®)
3.5 RESPIRATORY STIMULANTS
3.5.1 Respiratory Stimulants
Doxapram

3.5.2 Pulmonary Surfactants
Poractant

3.7 MUCOLYTICS
Dornase alfa
by safe and clinically effective practice 3.8 INHALATIONS
No recommendations
3.9 ANTITUSSIVES
3.9.1 Cough Suppressants

Pholcodine linctus
Dextromethorphan

3.9.2 Expectorant & Demulcent Preparations
Simple linctus
CHAPTER 4: CENTRAL NERVOUS SYSTEM

Many drugs in chapter 4 are initiated on advice of Mental Health specialists (e.g. HFT) and it is
expected that patients may be continued on these or treatment may be initiated on them on advice of a
Mental Health specialist
4.1 HYPNOTICS AND ANXIOLYTICS
4.1.1 Hypnotics

Temazepam
Loprazolam
Continuation of GP initiated treatment only Continuation of GP initiated treatment only Clomethiazole (Chlormethiazole)
These agents will not normally be supplied on discharge

4.1.2 Anxiolytics
Buspirone hydrochloride
Mental Health advice or Continuation of treatment only
4.1.3 Barbiturates
Specialist Use Only & E.E.G.

4.2 DRUGS USED IN PSYCHOSES AND RELATED DISORDERS
4.2.1 Antipsychotic Drugs
Amisulpride
Mental Health advice or Continuation of treatment only advice or Continuation of treatment only Mental Health advice or Continuation of treatment only Mental Health advice or Continuation of treatment only Psychogeriatrician or Mental Health advice / continuation Neurologists or Mental Health advice / continuation Mental Health advice or Continuation of treatment only Mental Health advice or Continuation of treatment only Other agents not recommended and only available if recommended by a Mental Health specialist

4.2.2 Antipsychotic Depot Injections *All agents Specialist Use Only*

4.2.3 Antimanic Drugs
Specify brand of product*

Lithium Carbonate (Camcolit ) Lithium Citrate (Priadel Liquid) Carbamazepine see section 4.8.1
Valproic acid (as semisodium valproate) (e.g. Depakote®)

4.3 ANTIDEPRESSANTS
4.3.1 Tricyclic and Related Antidepressants
Amitriptyline
Dosulepin (Dothiepin)
Mental Health advice or Continuation of treatment only Mental Health advice or Continuation of treatment only Mental Health advice or Continuation of treatment only Mental Health advice or Continuation of treatment only RELATED ANTIDEPRESSANTS Trazodone
4.3.2 Monoamine Oxidase Inhibitors
No recommendations – only available if recommended by Mental health specialist
4.3.3 SSRIs and related
Fluoxetine

4.3.4
Duloxetine (Cymbalta®)
Endocrinology/Neurology & Pain Team Use Mental Health advice or Continuation of treatment only 4.4 CENTRAL NERVOUS STIMULANTS
Atomoxetine
Dexamfetamine
Methylphenidate
Modafinil
Lisdexamfetamine

Advice or Continuation of Treatment only
4.5 APPETITE SUPPRESSANTS
No recommendations
4.5.2 CENTRALLY-ACTING APPETITE SUPPRESSANTS
No recommendations

4.6 DRUGS USED IN NAUSEA AND VERTIGO

Cinnarizine
Promethazine Chlorpromazine see 4.2.1 Haloperidol see 4.2.1 Levomepromazine (Methotrimeprazine) see 4.2.1 Prochlorperazine 5-HT3 ANTAGONISTS Ondansetron NEUROKININ RECEPTOR ANTAGONISTS Aprepitant
OTHER DRUGS
Betahistine
Hyoscine Hydrobromide
4.7 ANALGESICS
4.7.1 Non Opioid Analgesics
Paracetamol
Co-codamol 8/500
Co-codamol 30/500
Ibuprofen see 10.1.1
Paracetamol I/V
4.7.2 Opioid Analgesics

Codeine
NOT for under 12 years old or breastfeeding mothers
Tramadol
STRONG OPIOIDS

Diamorphine Fentanyl patches Fentanyl patches (chronic non cancer pain) 2nd line after oral morphine failure Fentanyl buccal tablets (Effentora®) by palliative care/Renal/pain specialists
4.7.3 Neuropathic pain
Carbamazepine
Amitriptyline
Sodium Valproate
Pain Team – Consultant use only, for chronic neuropathic pain Pain Team – Consultant use only, for chronic neuropathic pain 4.7.4 Antimigraine Drugs
4.7.4.1 Treatment of Acute Migraine Attack
Aspirin

4.7.4.2 Prophylaxis of Migraine
Propranolol

4.8 ANTI-EPILEPTICS
4.8.1 Control of Epilepsy

Phenytoin
Sodium valproate (including S/R e.g. Epilim Chrono®)
Carbamazepine
Phenobarbital
Lamotrigine Levetiracetam Lacosamide Ethosuximide
4.8.2 Drugs Used in Status Epilepticus
Lorazepam
Phenytoin

Clonazepam
Paraldehyde
Phenobarbital
Midazolam Buccal

4.9 DRUGS IN PARKINSONISM AND RELATED DISORDERS
4.9.1 Dopaminergic Drugs

Co-beneldopa (Madopar)
Co-careldopa (Sinemet
)
Duodopa®
Amantadine
Apomorphine

Ropinirole Ropinrole SR Selegiline Levodopa + carbidopa + entacapone (Stalevo ) Rotigotine Patches
4.9.2 Antimuscarinic Drugs
Trihexyphenidyl

4.9.3 Drugs Used in Tremor and Related Disorders.
Botulinum A Toxin Complex
Botulinum B Toxin


4.10 DRUGS USED IN SUBSTANCE DEPENDENCE
Alcohol dependence

See Guidelines
dependence
Guidelines
Acamprosate Lofexidine Methadone Buprenorphine Mental Health advice or continuation of treatment only Naltrexone Mental Health advice or continuation of treatment only
Nicotine patches, nicotine mini lozenges and inhalators
Bupropion
Varenicline
4.11 DRUGS FOR DEMENTIA
Memantine
Donepezil

Galantamine Galantamine SR. Rivastigmine (oral & patches)
CHAPTER 5: INFECTIONS

All drugs in italics must be recommended by a Consultant Microbiologist or Consultant in Infectious Disease, unless otherwise stated.
5.1 ANTIBACTERIAL DRUGS
5.1.1 Penicillins
Benzylpenicillin

intravenous treatment
Penicillin V
(Phenoxymethylpenicillin)

5.1.1.2 Penicillinase - resistant Penicillins
Flucloxacillin

Consultant in Infectious Diseases or Microbiology
5.1.1.3 Broad-Spectrum Penicillins
Amoxicillin
Co-amoxiclav
5.1.1.4 Antipseudomonal Penicillins

Piperacillin/Tazobactam

Consultant in Infectious Diseases or Microbiology
5.1.1.5 Mecillinams
Pivmecillinam Hydrochloride
Consultant in Infectious Diseases or Microbiology

5.1.2 CEPHALOSPORINS AND BETA-LACTAMS
CEPHALOSPORINS
Cefradine (Cephradine)
Cefotaxime
intravenous treatment
Consultant in Infectious Diseases or Microbiology Consultant in Infectious Diseases or Microbiology Consultant in Infectious Diseases or Microbiology Infectious Diseases Consultants in OUTPATIENTS only
5.1.3 TETRACYCLINES
Tetracycline
Doxycycline
Demeclocycline
Consultant in Infectious Diseases or Microbiology recommendation only
5.1.4 AMINOGLYCOSIDES
Gentamicin
Netilmicin
Respiratory specialist (when patient
5.1.5 MACROLIDES
Clarithromycin

5.1.6 CLINDAMYCIN
Clindamycin
Cellulitis (if patient Penicillin sensitive)
5.1.7 OTHER ANTIBIOTICS
Sodium Fusidate/ Fusidic Acid
Consultant in Infectious Diseases or Microbiology for IV preparation In line with SMC guidance recurrent C.Difficile only

5.1.8 SULPHONAMIDES AND TRIMETHOPRIM
Trimethoprim

5.1.9 ANTITUBERCULOUS DRUGS
Specialist recommendation - See BNF for appropriate drugs

5.1.10 ANTILEPROTIC DRUGS
Specialist recommendation - See BNF for appropriate drugs

5.1.11 METRONIDAZOLE

Metronidazole
5.1.12 QUINOLONES

Ciprofloxacin
Ofloxacin
Consultant only (after discussion with Microbiology) Or Consultant Respiratory Physician
5.1.13 URINARY TRACT INFECTIONS

Nitrofurantoin
Trimethoprim see 5.1.8
Methenamine hippurate

5.2 ANTIFUNGAL DRUGS
Fluconazole

Nystatin oral/topical
Amphotericin
Haematology or Consultant Microbiologist/Infectious Diseases Haematology or Consultant Microbiologist/Infectious Diseases Amphotericin(lipid complex) Haematology or Consultant Microbiologist/Infectious Diseases Caspofungin Haematology Anidulafungin Voriconazole
Clotrimazole Preparations see Section 7.2.2 and 13.10.2
5.3 ANTIVIRAL DRUGS
Aciclovir
HUMAN IMMUNODEFICIENCY VIRUS NRTI Didanosine Atripla Abacavir Emtricitabine Lamivudine PI Amprenavir Atazanavir Indinavir Nelfinavir NNRTI Efavirenz Etravirine Nevirapine Adefovir dipivoxil Enfuvirtide Maraviroc Raltegravir Foscarnet Ganciclovir Valganciclovir Oseltamivir Prophylaxis during Influenza A outbreaks Zanamivir Palivizumab Entecavir Telaprevir Rilpivirine
5.4 ANTIPROTOZOAL DRUGS
Specialist recommendation - See BNF for appropriate drugs – includes tinidazole

Artemether with lumefantine (Riamet ) Consultant in Infectious Diseases

5.5 ANTIHELMINTICS
Specialist recommendation - See BNF for appropriate drugs
CHAPTER 6: ENDOCRINE SYSTEM

6.1. DRUGS USED IN DIABETES
6.1.1 Insulin
6.1.1.1 Short Acting Insulins
Human Actrapid
Humulin S
Pork Actrapid
Humulin R

Insulin Lispro
Insulin Aspart
Insulin Glulisine
Insuman rapid
6.1.1.2 Intermediate & Long Acting insulins
Human Insulatard
Humulin I
Porcine Insulatard
Human Monotard
Human Ultratard
Insuman Basal
Insulin Glargine
Biphasic Insulins
Pork Mixtard 30
Human Mixtard 30, 50
Humulin M3, M5
Biphasic Insulin Aspart
Humalog Mix25
Humalog Mix 50
Insuman Comb
Insulin Detemir
6.1.2 Oral antidiabetic Drugs
6.1.2.1 Sulphonylureas

Gliclazide
Tolbutamide
Glibenclamide
Glimepiride

6.1.2.2 Biguanides
Metformin tablets & sachets
Metformin SR tablets

6.1.2.3 Other Antidiabetics
Lixisenatide

Specialist use only as per guidelines Specialist use only as per guidelines Specialist use only as per guidelines Pioglitazone/metformin (Competact )
Sitagliptin
Saxagliptin
Dapagliflozin

6.1.4 Treatment of Hypoglycaemia
Dextrose (Hypostop)
Glucagon

6.2. THYROID AND ANTITHYROID DRUGS
6.2.1 Thyroid hormones
Levothyroxine
Liothyronine
6.2.2 Antithyroid Drugs
Carbimazole

6.3. CORTICOSTEROIDS
6.3.1 Replacement Therapy
Fludrocortisone
6.3.2 Glucocorticoid Therapy
Prednisolone
Dexamethasone Hydrocortisone Methylprednisolone Betamethasone
6.4 SEX HORMONES
6.4.1 Female sex hormones
OESTROGEN + PROGESTOGEN PREPARATIONS
Conjugated Oestrogens (Premarin ) Estradiol Estradiol hemihydrate (Aerodiol ) Tibolone RALOXIFENE Raloxifene
6.4.1.2 Progestogens
Dydrogesterone

6.4.2 Male Sex Hormones & Antagonists
Testosterone (e.g. implants, Sustanon®, Nebido®)
Testosterone gel (Tostran®2%)

ANTI-ANDROGENS
Cyproterone

6.5 HYPOTHALMIC & PITUITARY HORMONES & ANTI-OESTROGENS
6.5.1 Hypothalmic and Anterior pituitary hormones and antioestrogens
ANTIOESTROGENS
Clomifene
Thyrotropin Alfa (Thyrogen®) ANTERIOR PITUITARY HORMONES CORTICOTROPHINS Tetracosactide (Synacthen ) GONADOTROPHINS HYPOTHALAMIC HORMONES Gonadorelin
6.5.2 Posterior Pituitary Hormones & Antagonists
Argipressin (Synthetic Vasopressin)
Desmopressin
Terlipressin Acetate
Tolvaptan Restricted to Consultant Endocrinologists/Consultant Oncologists

ANTI-DIURETIC HORMONE
Demeclocycline see section 5.1.3

6.6. DRUGS AFFECTING BONE METABOLISM
6.6.1 Calcitonin
and parathyroid hormone
Calcitonin (salmon)
Teriparatide

6.6.2 Bisphosphonates
Etidronate & Calcium combination pack Alendronate Zoledronic acid injection (Zometa ) Zoledronic acid infusion (Aclasta®) Ibandronic acid oral (Bondronat ) Haematology/Oncology Ibandronic acid injection (Bonviva ) Metabolic Bone/Endocrinology/Rheumatology

6.7. OTHER ENDOCRINE DRUGS
6.7.1 Bromocriptine and other Dopamine Receptor stimulants
Bromocriptine

6.7.2. Drugs affecting Gonadotrophin
Danazol
GOSERELIN ANALOGUES
Nafarelin Triptorelin (Decapeptyl® SR) CHAPTER 7: OBSTETRICS, GYNAECOLOGY, AND
URINARY TRACT DISORDERS

7.1 DRUGS USED IN OBSTETRICS
7.1.1. Prostaglandins & Oxytocics

Dinoprostone
Carboprost
Oxytocin with ergometrine (Syntometrine )
Misoprostol
Carbetocin

7.1.1.1 Ductus Arteriosus
MAINTENANCE OF PATENCY
Alprostadil
CLOSURE OF DUCTUS Indometacin Ibuprofen I/V
7.1.2 Mifepristone
SPECIALIST USE ONLY

7.1.3 Myometrial Relaxants
Ritodrine
Atosiban

7.2 TREATMENT OF VAGINAL AND VULVAL CONDITIONS
7.2.1 Preparations for Vaginal Atrophy
Topical Oestrogens.
Vagifem
7.2.2 Anti infective Drugs (Topical)
CANDIDIASIS
Clotrimazole
Cream/Pessary
Miconazole OTHER INFECTIONS Acetic acid 0.92% Vaginal jelly Clindamycin Vaginal Cream Metronidazole Vaginal Cream Nystatin Vaginal Cream 7.3 CONTRACEPTIVES
7.3.1.Combined Oral Contraceptives
LOW STRENGTH
Levonelle-2
7.3.2.1 Oral Progestogen-only Contraceptives
Norethisterone

7.3.2.2 Parenteral progestogen-only contraceptives

7.3.2.3 Intra-uterine progestogen-only contraceptive
Etonogestrel Implant (Implanon )
7.3.4. Intrauterine Contraceptive Devices
Nova T 380

7.4 DRUGS FOR GENITO-URINARY DISORDERS
7.4.1 Drugs for urinary retention
ALPHA-BLOCKERS
Terazosin
7.4.2 Drugs for urinary frequency and incontinence
URINARY INCONTINENCE
Oxybutynin Tablets
Oxybutynin XL
Tolterodine
Duloxetine (e.g.Yentreve ) Obstetrics and Gynaecology Oxybutynin Transdermal Patch (Kentera) Oxybutynin Fesoterodine Fumerate (Toviaz)
Mirabegron
7.4.3 Urological Pain
Potassium Citrate
Cystistat Bladder Wash

7.4.4 Bladder instillations
Chlorhexidine bladder washes
Solution-G bladder washes
Sodium Chloride 0.9% bladder washes
Solution-R bladder washes
7.4.5 Drugs for Impotence
Sildenafil
Alprostadil (Viridal ) Apomorphine (sublingual) Papaverine Vardenafil (Levitra )
Tadalafil

CHAPTER 8: MALIGNANT DISEASE AND
IMMUNOSUPPRESION

8.1 CYTOTOXIC DRUGS
All items in italics are Specialist Use ONLY, and should only be prescribed by
Consultant Oncologist, Haematologist and their teams.
Disodium folinate

8.1.1 Alkylating Agents

Cyclophosphamide

Bendamustine
Busulfan
Carmustine
Carmustine Implant


8.1.2 Cytotoxic Antibiotics
Bleomycin
(Caelyx or Myocet® depending on indication) Doxorubicin and DC beads (for precision TACE) Epirubicin
8.1.3 Antimetabolites
Mercaptopurine
Methotrexate
Capecitabine
Cladribine

Cytarabine Liposomal Cytarabine Fludarabine Gemcitabine Tioguanine (Thioguanine) Pemetrexed Available on chairs approval in accordance with TA 61
8.1.4 Vinca Alkaloids and etoposide
Etoposide
Vinblastine

Vindesine
Vinorelbine
8.1.5 Other Antineoplastic agents
Azacytidine (Vidaza)
Amsacrine
Bevacizumab
Bexarotene

PbR excluded. PCT treatment exemption panel approval required Bortezomib Carboplatin Cetuximab Cisplatin Dacarbazine Dasatinib Docetaxel Erlotinib Gefitinib Hydroxycarbamide (Hydroxurea) Imatinib Irinotecan Ipilimumab Nilotinib Paclitaxel Pazopanib Procarbazine Sunitinib Temozolamide Topotecan Trastuzumab Tretinoin Trabectedin Use in line with NICE TA185 & Cancer Network Guidelines Vemurafenib Use in line with NICE TA269 & Cancer Network Guidelines National Cancer Drugs Fund List 2013
Indication
Abiraterone
1st line treatment of metastatic castrate resistant prostate cancer (Mcrpc) in adult men who are asymptomatic, or mildly symptomatic, after failure of androgen deprivation therapy (ADT) in whom chemotherapy is not yet clinically indicated Axitinib
Option for 2nd line advanced renal cell carcinoma with progression after TKI or a cytokine Bendamustine
2nd or subsequent line treatment of CLL for patients whom fludarabine combination therapy is not a therapeutic option. Treatment of relapsed low grade NHL in patients unable to receive standard chemotherapy. 1st line treatment of low grade non-hodgkins lymphoma in combination with rituximab Treatment of relapsed low grade/indolent NHL refractory to rituximab based regimens 2nd and subsequent line treatment of mantle cell lymphoma in patients who have not received previous bendamustine 1st line treatment of mantle cell lymphoma in combination with rituximab in patients unsuitable for standard first line treatment Treatment of relapsed multiple myeloma where other treatments are not appropriate Bevacizumab
Treatment of patients with triple negative metastatic breast cancer and/or prior taxane therapy 1st line treatment of metastatic colorectal cancer. Only to be administered concurrently with chemotherapy, not as single agent maintenance therapy. 2nd line treatment of metastatic colorectal cancer in combination with standard chemotherapy in patients who have not previously received bevacizumab. Only to be administered concurrently with chemotherapy, not as single agent maintenance therapy. 3rd line treatment of metastatic colorectal cancer in combination with standard chemotherapy in patients who have not previously received bevacizumab. Only to be administered concurrently with chemotherapy,not as single agent maintenance therapy. 1st line treatment of advanced (stage IIIc/IV) ovarian cancer, sub-optimally debulked either at primary or delayed primary (interval) surgery (including peritoneal and fallopian tube cancer) OR unsuitable for debulking surgery. Botezomib
Treatment of relapsed or refractory multiple myeloma at second and subsequent relapse in patients who are botezomib naïve and where the patient unable to access bortezomib at first relapse. Treatment of relapsed or refractory multiple myeloma at second and susbsequent relapse in patients with previous good response to bortezomib. Treatment of 2nd or subsequent relapse in Refractory Mantle cell Lymphoma, in patients not fit for transplant Treatment of relapsed Waldenstrom’s macroglobulinaemia after previous treatment with standard chemotherapy Brentuximab
Treatment of relapsed or refractory Hodgkins lymphoma in patients who have failed at least two prior multi-agent chemotherapy regimens and are not ASCT candidates As a bridge to allograft transplant for the treatment of Hodgkin’s Lymphoma where no other salvage treatment is available As a bridge to allograft transplant for the treatment of anaplastic large cell lymphoma where no other salvage treatment is available Cabazitaxel
2nd line treatment of advanced castration resistant prostate cancer following docetaxel based regimen 3rd line treatment of advanced castration resistant prostate cancer following docetaxel and abiraterone based treatment Cetuximab
1st line treatment of metastatic and/or recurrent squamous cell carcinoma of the head and neck Treatment of KRAS wild-type metastatic colorectal cancer in any indication outside of NICE TA176, in patients who have not previously received cetuximab up to progression Clofarabine
Acute myeloblastic leukaemia in patients with relapsed/refractory disease in whom the intent is to use treatment as a bridge to bone marrow transplantation Acute lymphoblastic leukaemia in patients with relapsed/refractory disease in whom the intent is to use treatment as a bridge to bone marrow transplantation Crizotinib
In second and subsequent line anaplastic lymphoma kinase (ALK) – positive advanced non -small lung cancer Dasatinib
Treatment of adults with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL) with resistance or intolerance to prior therapy including Imatinib Treatment of adults with Philadelphia chromosome positive (Ph+) lymphoid blast CML with resistance or intolerance to prior therapy including Imatinib 2nd line treatment of chronic, accelerated or blast phase CML patients with intolerance to imatinib mesilate, and who are intolerant of nilotinib Eribulin
Treatment of patients with locally advanced or metastatic breast cancer who have been previously treated with (or unsuitable for ) an anthracycline, a taxane and capecitabine Everolimus
2nd line treatment of metastatic renal cell carcinoma where disease has progressed on or after treatment with VEGF- targeted therapy or where patient has a contra-indication to or is intolerant of VEGF –targeted therapy 1st line treatment of unresectable or metastatic, well- or moderately-differentiated neuroendocrine tumours of pancreatic origin in adults with progressive disease 2nd line treatment of unresectable or metastatic, well-or moderately-differentiated neuroendocrine tumours of pancreatic origin in adults with progressive disease 2nd line treatment of hormone receptor +ve, HER2 negative advanced breast cancer, in combination with exemestane, in post menopausal women without symptomatic visceral disease after recurrence or progression following a non steroidal aromatase inhibitor who have not received previous exemestane Imatinib
Adjuvant treatment of gastro-intestinal stromal tumours (GIST), in patients considered high risk of relapse (based on risk criteria or mutation analysis), for up to 3 years Lapatinib
2nd and subsequent line use in combination with capecitabine for the treatment of patients with locally recurrent or metastatic breast cancer, whose tumours over express HER2(ErbB2) and whose disease has progressed on trastuzumab Lenalidomide
2nd line treatment of multiple myeloma in patients who have contraindications to the use of bortezomib Nelarabine
Treatment of refractory T-cell lymphoblastic non-Hodgkin’s Lymphoma as a bridge to bone marrow transplantation Treatment of refractory T-cell acute lymphoblastic leukaemia as a bridge to bone marrow transplantation Ofatumumab
2nd line treatment of chronic lymphocytic leukaemia (CLL) in patients who are refractory to fludarabine and ineligible/unsuitable for alemtuzumab 2nd line treatment of CLL in patients with p53 mutation who relapse or progress on first line alemtuzumab and are not suitable for fludarabine 3rd line treatment of CLL in patients refractory to fludarabine and alemtuzumab Pazoponib
Third line treatment of metastatic non-adipocytic soft tissue sarcoma Pegylated Liposomal
1st line treatment of angiosarcoma, especially cutaneous Doxorubicin (Caelyx)
2nd line treatment of angiosarcoma, especially cutaneous 1st line treatment of primary sarcoma of the heart and great vessels 1st line treatment of sarcoma in patients with cardiac impairment who need an anthracycline 2nd line treatment of sarcoma in patients with cardiac impairment who need an anthracycline 2nd line treatment of fibromatosis Pemetrexed
2nd line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology in patients who did not receive 1st line pemetrexed e.g. 1st line clinical trial Maintenance treatment of stage IIIB/IV non-squamous non-small cell lung cancer after response to pemetrexed-containing first line therapy Peptide receptor
Treatment of advanced neuroendocrine tumours i.e. for pNETS Radionucleotide Therapy
after sunitinib/Chemotherapy, For mid-gut Carcinoid, after to include Lutetium 177
Octreotate or Yttrium90
octreotide/octreotate
Ruxolitinib

1st line treatment of symptomatic splenomegaly in adult patients with primary myelfibrosis, post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis. For new patients only 2nd line treatment of symptomatic splenomgaly in adult patients with primary myelfibrosis, post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis. For new patients only Sorafenib
1st line treatment of advanced hepatocellular carcinoma in patients with Childs A disease 1st line treatment of advanced hepatocellular carcinoma in patients with low disease burden Childs B disease Treatment of papillary or follicular thyroid cancer that is inoperable or metastatic disease that is refractory to radioiodine Sunitinib
1st line treatment of unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumour with disease progression 2nd line treatment of unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumour with disease progression 3rd line treatment of unresectable or metastatic, well-differentiated pancreatic neuroendocrine tumour with disease progression Temsirolimus
1st line treatment of patients with advanced renal cell carcinoma (RCC) who have at least three of six prognostic risk factors. Vandetinib
Treatment of symptomatic, locally advanced (unresectable) or metastatic medullary thyroid cancer.

8.2 DRUGS AFFECTING THE IMMUNE RESPONSE
8.2.1 Cytotoxic Immunosuppressants
Azathioprine

8.2.2 Corticosteroids and other immunosuppressants
Ciclosporin (Cyclosporin)
Prednisolone
Sirolimus Specialist Use/Transplant Tacrolimus
8.2.3 Anti-lymphjocyte monoclonal antibodies
Rituximab
Alemtuzumab Haematologists and Oncologists

8.2.4 Interferons
Interferon
Peginterferon alfa Natalizumab Fingolimod Use in line with NICE TA228 & Cancer Network Guidelines
8.3 SEX HORMONES AND HORMONE ANTAGONISTS
IN MALIGNANT DISEASE

8.3.1 Oestrogens
Diethylstilbestrol
8.3.2 Progestogens
Medroxyprogesterone

8.3.4 Hormone Antagonists
8.3.4.1 Breast Cancer
Tamoxifen
Aminoglutethimide
Anastrazole
Exemestane
Letrozole
Fulvestrant

8.3.4.2 Prostate Cancer
Abiraterone Acetate
Cyproterone
Goserelin
Flutamide
Bicalutamide
Degarelix
8.3.4.3 Somatostatin analogues
Octreotide
Lanreotide
CHAPTER 9: NUTRITION AND BLOOD

9.1 ANAEMIAS & SOME OTHER BLOOD DISORDERS
9.1.1.1 Oral Iron
Ferrous Sulphate
Ferrous Fumarate

9.1.1.2 Parenteral Iron

Iron sucrose complex (Venofer®) IV
infusion
Iron dextran (Cosmofer®) Iron (III) Isomaltoside 1000 (Monofer®) Approved for Renal Medicine & Cardiac Surgery
9.1.2 Drugs used in megaloblastic anaemias
Hydroxocobalamin

9.1.3 Drugs used in hypoplastic, haemolytic & renal anaemias
Darbepoetin Alfa
Epoetin

IRON OVERLOAD
Desferrioxamine
9.1.4 Drugs used in platelet disorders
Anagrelide
Romiplostim

Use in line with NICE TA221 & Cancer Network Guidelines
9.1.6 Drugs used in neutropenia
Filgrastim
Pegfilgrastim
Lenograstim


9.2 FLUIDS & ELECTROLYTES
9.2.1 Oral Administration
9.2.1.1 Oral Potassium
Sando K

Kay- Cee- L Liquid

Potassium Chloride SR (Slow-K )
POTASSIUM REMOVAL
Calcium resonium

9.2.1.2 Oral Sodium and Water
Sodium Chloride
ORAL REHYDRATION SALTS
Dioralyte

9.2.1.3 Oral Bicarbonate
Sodium
9.2.2 Parenteral Fluids.
Sodium Chloride 0.9%
Dextrose 5%
Hartmann’s Solution
Ringers Solution
Dextrose 4% & Sodium Chloride 0.18%
Dextrose 10% & Sodium Chloride 0.18%
Dextrose 10% with Potassium
for glucose potassium insulin (GKI) infusion Dextrose 5% with range of potassium strengths Sodium Chloride 0.9% with range of potassium strengths Potassium Chloride 15%
SODIUM BICARBONATE
Sodium Bicarbonate 1.26%
Sodium Bicarbonate 8.4%

All other fluids only available on specific requests
9.2.2.2 Plasma Substitutes
Gelatin (Volplex®)


Hydroxyethyl starch (Voluven®)
Albumin
Volulyte

9.3 INTRAVENOUS NUTRITION
Seek Specialist Advice from nutrition team
As contract specified

9.4 ENTERAL NUTRITION
Pre-op
Seek Specialist Advice from Dietetics department.
As contract specified

9.5 MINERALS
9.5.1.1 Calcium Supplements
Sandocal-

Sandocal-
Parenteral - Calcium Chloride or Calcium Gluconate 9.5.1.2 Hypercalcaemia and hypercalciuria.
Cinacalcet
9.5.1.3 Magnesium Supplements
Parenteral - Magnesium Sulphate
Magnaspartate Sachets
9.5.2 Phosphorus
Phosphate-Sandoz
Sodium Phosphate Oral Solution
9.5.2.2 Phosphate-binding Agents
Calcium Acetate
Aluminium
Sevelamer (Renagel®) Sevelamer (Renvela®) Powder Sachets Only Lanthanum Carbonate
9.5.3 Fluoride
Duraphat Toothpaste 2800 ppm (Sodium Fluoride 0.619%)
9.5.4 Zinc
Zinc Sulphate

9.5.5 Selenium
Selenium
9.6 VITAMINS
9.6.1 Vitamin A

Vitamin

9.6.2 Vitamin B group
Thiamine (B1)
Vitamin B Compound Strong
9.6.3 Vitamin C
Ascorbic acid

9.6.4 Vitamin D
Alfacalcidol
Calcium & Vitamin D (Calcium and Ergocalciferol tablets)
Calcium carbonate 1.25 g (calcium 500 mg) & colecalciferol 10 micrograms (Calceos®)
Calcium carbonate 1.5g (calcium 600mg) & colecalciferol 10 micrograms (Adcal – D3®)
Ergocalciferol injection
Paricalcitol
Colecalciferol (Fultium D3)
9.6.5 Vitamin E
Alpha Tocopheryl acetate
Vitamin E Suspension
9.6.6 Vitamin K
Menadiol sodium phosphate
Phytomenadione
9.6.7 Multivitamin preparations
Multivitamins
Forceval®
Sanatogen A-Z complete®

9.8.1 Wilson’s Disease
Penicillamine
Carnitine deficiency
Carnitine

CHAPTER 10: MUSCULOSKELETAL AND JOINT
DISEASES

10.1 DRUGS USED IN RHEUMATIC DISEASE AND GOUT

10.1.1 Non-steroidal anti-inflammatory drugs.
Ibuprofen

Diclofenac
(Dyloject®)
Ketoprofen gel (Ibuprofen gel 5% due to manufacturing problem) Mefenamic acid Naproxen Celecoxib
10.1.2 Corticosteroids
10.1.2.1 Systemic Corticosteroids

10.1.2.2 Local Corticosteroid injection
Dexamethasone sodium phosphate

10.1.3 Drugs which suppress the rheumatic disease process
GOLD
Sodium Aurothiomalate
PENICILLAMINE
Penicillamine
Dermatology/Rheumatology/Gastroenterology Rheumatologist/Gastroenterologists

10.1.4 Drugs for treatment of gout

ACUTE ATTACKS
Non-steroidal anti-inflammatory drugs see section 10.1.1
Colchicine
INTERVAL TREATMENT Allopurinol Febuxostat Probenecid
Rasburicase
10. 2 DRUGS USED IN NEUROMUSCULAR DISORDERS
10.2.1 Drugs which enhance neuromuscular transmission

ANTICHOLINESTERASES
Neostigmine

10.2.2 Skeletal muscle relaxants
Baclofen

DRUGS FOR THE RELIEF OF SOFT-TISSUE INFLAMMATION
10.3.1 Enzymes
Hyaluronidase

10.3.2
Rubefacients and other topical antirheumatics
Capsaicin Cream
Transvasin Cream
TOPICAL NSAID’S
Ketoprofen gel
Movelat
POULTICES
Kaolin poultice
CHAPTER 11: EYE

Products identified as specialist use products should only be prescribed after recommendation by a
Consultant or Specialist Registrar in Ophthalmology.

11.3 ANTI-INFECTIVE EYE PREPARATIONS
11.3.1 Anti-bacterials
Ofloxacin Eye Drops
Chloramphenicol Eye-drops and Eye Ointment
Fusidic acid Viscous Eye Drops
Gentamicin Eye drops
Chlortetracycline Eye ointment
Benzylpenicillin

11.3.2 Antifungals

Clotrimazole Eye drops Named patient
11.3.3 Antivirals
Aciclovir Eye Ointment
Trifluorothymidine Eye Drops Named patient
CORTICOSTEROIDS AND OTHER ANTI-INFLAMMATORY.
11.4.1 Corticosteroids
Prednisolone Eye Drops
Dexamethasone Eye Drops
Betamethasone Eye Drops and Eye Ointment
Fluorometholone Opthalmic Suspension
Maxitrol Eye drops
Rimexolone Eye drops
Tobramycin 0.3%/Dexamethasone 0.1% (Tobradex ) Ciclosporin (Cyclosporin) Eye Drops Bromfenac Sodium sesquihydrate (Yellox®) eye drops Dexamethasone intravitreal implant
Fluocinolone Acetonide (Iluvien®)Intravitreal Implant

11.4.2 Other anti-inflammatory preparations
Nedocromil Sodium Eye Drops
Sodium Cromoglicate Eye Drops
Levocabastine Eye Drops
Olopatadine


11.5 MYDRIATICS AND CYCLOPLEGICS
ANTIMUSCARINICS
Cyclopentolate Eye Drops
Atropine Sulphate Eye Drops
Tropicamide Eye Drops
Homatropine Eye Drops
SYMPATHOMIMETICS
Phenylephrine Eye Drops

11.6 TREATMENT OF GLAUCOMA
BETA-BLOCKERS
Timolol Eye Drops
Timolol Gel solution (Long-acting)
Betaxolol Eye Drops
PROSTAGLANDIN ANALOGUES AND PROSTAMIDES
Latanaprost & Latanoprost PF Eye-drops
Travoprost Eye drops
Bimatoprost & Bimatoprost PF Eye drops
Prostaglandin Analogues with Timolol
Latanoprost with Timolol
Travoprost 40micrograms/Timolol 5mg per ml (DuoTrav®)
Bimatoprost with Timolol (Ganfort®)
SYMPATHOMIMETICS
Brimonidine Eye drops

CARBONIC ANHYDRASE INHIBITORS AND SYSTEMIC DRUGS
Acetazolamide Injection and Capsules
Dorzolamide Eye Drops
Carbonic anhydrase inhibitors with Timolol
Dorzolamide 2% / Timolol 0.5% eye drops
Brinzolamide 10mg / Timolol 5mg per ml (Azarga®)

MIOTICS
Pilocarpine Eye Drops


11.7 LOCAL ANAESTHETICS
Tetracaine (Amethocaine) Eye Drops
Oxybuprocaine Eye drops
Lidocaine (Lignocaine) with Fluorescein Eye Drops
Proxymetacaine Eye Drops

11.8 MISCELLANEOUS OPTHALMIC PREPARATIONS

11.8.1 Tear Deficiency, Ocular Lubricants, and astringents
Hypromellose Eye Drops
Polyethylene Glycol 400 0.4%, propylene glycol 0.3%, hydroxypropyl guar (Systane®)
Carmellose (Optive®) eye drops
Liquid Paraffin (Lacrilube ) Eye Ointment Carbomer (Polyacrylic Acid) Liquid Gel Polyvinyl alcohol Ophthalmic Solution Acetylcysteine eye drops (Ilube®) Sodium Hyaluronate (Artelac Rebalance®) Sodium Hyaluronate ( HYLO-forte®)
11.8.2 Ocular Diagnostic and Peri Operative Preparations and Photodynamic Treatment

AREDS Formula (e.g. Ocuvite® /Preservision ) Balanced Salt Solution and Balanced salt Solution Plus Diclofenac Ophtha Eye Drops Fluorescein Eye Drops and Fluorets HydroxyPropylMethylCellulose Eye Drops Acetylcholine (Miochol) Eye Drops Potassium Ascorbate Eye Drops Povidone Iodine 5% Minims – for peri-operative use Sodium Hyaluronate pfs (1ml) and (0.5ml) & Greater Viscosity (0.55ml) pfs Sodium hyaluronate + lidocaine (Visthesia )
Verteporfin
Aflibercept (Eylea®)
Ocriplasmin (Jetrea®)

11.9 CONTACT LENS PREPARATIONS
These products are not prescribable under the NHS, unless special exemption is obtained. Various
preparations are available for sale.
CHAPTER 12: EAR, NOSE, AND OROPHARYNX
AS PER BNF, CERTAIN PRODUCTS ARE LICENSED/APPROVED FOR BOTH AURAL
AND OCULAR USE. See BNF section 11 for more detail.

12.1 DRUGS ACTING ON THE EAR
12.1.1 Otitis externa.
ASTRINGENT PREPARATIONS
Aluminium Acetate Ear Drops
ANTI-INFLAMMATORY PREPARATIONS
Hydrocortisone with Gentamicin Ear Drops (Gentisone HC)
Betamethasone Ear Drops
Dexamethasone as Otomize Ear Drops
Prednisolone Ear Drops
Otosporin
ANTI-INFECTIVE PREPARATIONS
Gentamicin with Hydrocortisone Ear Drops (Gentisone HC)
Clotrimazole
Framycetin as Sofradex Ear Drops

12.1.3 Removal of ear Wax
Sodium bicarbonate Ear Drops
Olive Oil
12.2 DRUGS ACTING ON THE NOSE
12.2.1 Drugs used in Nasal Allergy
ANTIHISTAMINES
Azelastine Nasal Spray
CORTICOSTEROIDS
Beclometasone (Beclomethasone) Drops/ Nasal Spray
Budesonide Aqueous aerosol inhalation
Fluticasone Furoate (Avamys®)
Mometasone (Nasonex ) Sodium Cromoglicate nasal Spray Triamcinolone (Nasacort ) Nasal Spray
12.2.2 Topical Nasal Decongestant
Ephedrine Nasal Drops

12.2.3 Anti-infective nasal preparations
Mupirocin (Bactroban) nasal ointment
Chlorhexidine/Neomycin Nasal ointment (Naseptin
)

12.3 DRUGS ACTING ON OROPHARYNX
12.3.1 Drugs for oral ulceration and inflammation

Benzydamine Mouthwash, Spray
Bonjela gel
Hydrocortisone Oral pellets

12.3.2 Oropharyngeal Anti-infective Drugs
Nystatin
Amphotericin Lozenge
Miconazole oral gel

12.3.3 Lozenges Sprays and Gels
Dequalinium Lozenges

Tyrothricin with Benzocaine (Tyrozets )
12.3.4 Mouthwashes, gargles and Dentrifices
Chloraseptic Spray
Chlorhexidine
Mouthwash
Gelclair Oral Gel
Caphosol

12.3.5 Treatment of Dry Mouth
Glandosane Solution
Lemon Mouth Freshener
Thera-med 2 in 1 Liquid
Biotene Oral Balance Gel Pilocarpine tablets
CHAPTER 13: SKIN

13.2 EMOLLIENTS AND BARRIER PREPARATIONS
13.2.1 Emollients
Aqueous Cream
Balneum® Plus Cream
Doublebase® Gel
Emulsifying ointment in water
Zerocream® (E45 Cream substitute) Zerobase® (Diprobase substitute) Hydromol Cream and Ointment Liquid Paraffin 50% in Yellow soft paraffin Eczmol Cream
13.2.1.1 Emollient Bath Additives
Dermol Emollient
13.2.2 Barrier Preparations
Vasogen Cream
13.2.3 Dusting Powders
Talc and hexachlorophane Dusting powder
Talc Purified powder
13.3 TOPICAL LOCAL ANAESTHETICS AND ANTIPRURITICS
Tetracaine (Amethocaine) Cream
Calamine Lotion 
Crotamiton (Eurax ) Cream and Eurax HC Cream Pain relieving (PR) Aerosol spray Doxepin continuation
13.4 TOPICAL CORTICOSTEROIDS
Alclometasone (Modrasone) Ointment 0.05%
Betamethasone valerate Cream 0.1%, Cream 0.025% (1 in 4), Ointment 0.1%,
Ointment 0.025% (1 in 4), Foam for scalp (Bettamousse ) Betamethasone Dipropionate Ointment 0.05% Cream 0.05% Clobetasol propionate (Dermovate®) Cream 0.05%, Ointment 0.05% Clobetasol propionate (Etrivex ) Shampoo 0.05% Clobetasone butyrate (Eumovate ) Cream 0.05%, Fluocinolone acetonide (Synalar ) Cream 0.025%, Gel 0.025%, Ointment 0.025%, Cream 0.00625% (1 in 4), Ointment 0.00625% (1 in 4) Fluticasone propionate (Cutivate), Cream 0.05%, Ointment 0.005% Fludroxycortide (Haelan®) Tape Hydrocortisone Cream 0.5%, 1%, Ointment 0.5%, 1%, Hydrocortisone Lipocream 1% (Mildison®) Hydrocortisone butyrate (Locoid®) Cream 0.1%, Ointment 0.1%, Lipocream 1% Tri-adcortyl® Cream and Ointment Mometasone
With anti-bacterials
Betamethasone & clioquinol Cream and Ointment (formerly Betnovate C)
Locoid C® Cream and Ointment
Fucibet®

13.5 PREPARATIONS FOR ECZEMA AND PSORIASIS.
13.5.1 Preparations for eczema
Alitretinoin

13.5.2 Preparations for psoriasis

Alphosyl® Cream and Alphosyl HC
Balneum® with Tar Bath oil
Calcipotriol Cream and Ointment
Calcitriol Ointment
Sebco® scalp application
Coal Tar preparations:
The following “specials” used by Dermatology department:
Coal tar solution 5% in betnovate RD ointment
Gockermans ointment (this contains Crude oil tar 2% (or 4% or 6% or 10% or 20%), Zinc Oxide Newcastle Ointment. Available in a variety of strengths: Coal tar (9%), Salicyclic acid (3%), Tween (1%), Ung Emuls Compound ointment to 100% Coal tar (12%), Salicyclic acid (2%), Tween (1%), Ung Emuls Compound ointment to 100% Coal tar (6%), Salicyclic acid (2%), Tween (1%), Ung Emuls Compound ointment to 100% Coal tar (3%), Salicyclic acid (1%), Tween (1%), Ung Emuls Compound ointment to 100% Dithranol preparations: Dithrocream® Cream The following “specials” used by Dermatology department:  Dithranol in Lassars paste 0.25%, 0.5%, 0.1%, 1%, 2%, 4%, (w/v) Dithranol in Salicylic Acid 2% in emulsifying ointment 0.1%, 0.25%, 0.5%, 1%, 2% Dovobet ointment Dovobet® Scalp Gel Eosin in PMA 0.5% w/v Methoxypsoralen Paint, Gel and Bath lotion Polytar® Shampoo and Emollient Miconazole Cream 1% and 3% Tazarotene Gel Dithranol Cream in lipid-stabilised basis (Micanol ) ORAL RETINOIDS FOR PSORIASIS Acitretin Capsule OTHER PREPARATIONS FOR PSORIASIS Methoxypsoralen Emulsion
Methoxypsoralen Bath lotion
13.5.3 Drugs Affecting the Immune Response
Ciclosporin (Cyclosporin)
Methotrexate
Tacrolimus ointment
Pimecrolimus cream
Adalimumab
Etanercept
Ustekinumab


13.6 ACNE AND ROSACEA

13.6.1 Topical preparations for acne
Benzoyl peroxide Topical gels
Benzoyl peroxide and Adalpalene gel - Epiduo®
Benzamycin Gel
TOPICAL RETINOIDS FOR ACNE
Tretinoin Cream & Gel
Isotrexin Gel
13.6.2 Oral preparations for acne
Isotretinoin Capsule
Co-cyprindiol (Dianette ) Minocycline
13.7 PREPARATIONS FOR WARTS AND CALLUSES
Salicyclic acid preparations (Cuplex®, Verrugon®)
Salactol® Paint
Salatac® Gel
GENITAL WARTS
Podophyllum preparations
Warticon® Solution
Imiquimod
13.8 SUNSCREENS AND CAMOUFLAGERS
RoC® Total Sunblock Factor 25
Solaraze®
Methyl aminolevulinate cream (Metvix
®)
13.8.1 Sunscreen Preparations
Ingenol Mebutate (Picato®)
13.9 SHAMPOOS AND SOME OTHER SCALP APPLICATIONS
Alphosyl® Shampoo and 2 in1 Shampoo
Capasal® Shampoo
Ketoconazole 2% Shampoo
Polytar® and Polytar Plus® Shampoo
T/Gel® Shampoo
Eflornithine cream

13.10 ANTI-INFECTIVE SKIN PREPARATIONS
13.10.1.1 Antibacterial preparations only used topically
Mupirocin Ointment
Silver sulfadiazine (sulphadiazine) Cream
Polyfax Ointment
13.10.1.2 Antibacterial preparations also used systemically
Metronidazole Gel
13.10.2 Antifungal preparations
Clotrimazole Cream
Econazole Cream
Nystatin Cream
13.10.3 Antiviral preparations
Aciclovir Cream
13.10.4 Parasiticidal preparations
Carbaryl Lotion Use as local policy
Malathion Lotion Use as local policy
Dimeticone Lotion
Permethrin Cream rinse Use as local policy

13.10.5 Preparations for minor cuts and abrasions

Magnesium sulphate Paste
Proflavine Antiseptic cream
13.11 DISINFECTANTS AND CLEANSERS
See local guidelines from infection control team.
Triclosan (Aquasept® Solution/Skinsan Foam)
Chlorhexidine Preparations
Hydrogen peroxide Preparations
Hydrogen peroxide cream (Crystacide®)
Industrial Methylated Spirit Preparations
Manusept® Solution
Phisomed® Cleanser
Plaster Remover
Potassium permanganate (Permitabs®)
Povidone Iodine Preparations
Sodium Hypochlorite Preparations

13.11.7 Desloughing agents


13.13 TOPICAL CIRCULATORY PREPARATIONS

Hirudoid® Cream
Lasonil® Ointment

CHAPTER 14: IMMUNOLOGICAL PRODUCTS AND
VACCINES

For guidance on the choice and use of vaccines, see ‘Immunisation against infectious diseases’ a
HMSO publication – available online at:
http://www.dh.gov.uk/en/Publichealth/Healthprotection/Immunisation/Greenbook/DH_4097254

14.4 VACCINES AND ANTISERA
BCG Vaccine
Diphtheria Vaccine
Diphtheria/Tetanus Vaccine
Diphtheria/Tetanus/Pertussis Vaccine
Diphtheria Antitoxin
Haemophilus Influenzae Type b (Hib) Vaccine
Hepatitis A Vaccine
Hepatitis B Vaccine
Influenza Vaccine
Measles/Mumps/Rubella (MMR) Vaccine
Meningococcal Vaccine
Pertussis Vaccine (Whooping Cough)
Pneumococcal Vaccine
Poliomyelitis Vaccine Live
Poliomyelitis Vaccine Inactivated
Rotavirus Vaccine (Rotarix®)
Rubella Vaccine
Varicella-Zoster Vaccine
Varicella Vaccine (Varivax®)
Yellow Fever Vaccine
14.5 IMMUNOGLOBULINS
Normal Immunoglobulin (Brand dependant upon availability)
SPECIFIC IMMUNOGLOBULINS
Anti-human Thymocyte Immunoglobulin (Equine)
Human Anti-tetanus Immunoglobulin
Hepatitis B Immunoglobulin Dr Smithson
Anti-D (Rh(o)) immunoglobulin Haematology


CHAPTER 15: ANAESTHESIA

15.1 GENERAL ANAESTHESIA
15.1.1 Intravenous anaesthetics
BARBITURATES
Thiopental (Thiopentone) Sodium Injection
OTHER INTRAVENOUS ANAESTHETICS
Etomidate Injection
Ketamine Injection
Propofol Injection and Prefilled syringe
15.1.2 Inhalational anaesthetics
Sevoflurane
Isoflurane
Desflurane
15.1.3 Antimuscarinic drugs
Atropine Sulphate Injection
Glycopyrronium Injection
Hyoscine hydrobromide Injection
15.1.4 Sedative and analgesic peri-operative drugs
BENZODIAZEPINES
Midazolam Injection
Diazepam
Lorazepam
Temazepam Tablets
PHENOTHIAZINES AND RELATED
Promethazine see 3.4.1
15.1.4.2 Non-opioid analgesics
Diclofenac Sodium see 10.1.1
Ketoprofen injection see 10.1.1
Ketorolac Injection
Parecoxib injection
15.1.4.3 Opioid analgesics
Alfentanil Injection
Fentanyl Injection
Morphine Sulphate Injection
Pethidine Injection
Remifentanil Injection
15.1.5 Muscle Relaxants
NON-DEPOLARISING
Atracurium Besilate Injection
Cisatracurium Injection
Mivacurium Chloride Injection
Pancuronium Bromide Injection
Rocuronium Bromide Injection
Vecuronium Bromide Injection
DEPOLARISING
Suxamethonium Chloride Injection
15.1.6 Anti-cholinesterases used in anaesthesia
Neostigmine Injection
Edrophonium
Glycopyrronium-Neostigmine Injection
Sugammadex

15.1.7 Antagonists for central and respiratory depression
Flumazenil Injection
Naloxone Injection
15.1.8 Drugs used for malignant hyperthermia
Dantrolene Sodium Injection
15.2 LOCAL ANAESTHESIA
LIDOCAINE (LIGNOCAINE)
Lidocaine (Lignocaine) Injection
Lidocaine (Lignocaine) Plaster (Versatis ) Neuropathic pain in line with NICE CG96 Lidocaine 2.5% and prilocaine 2.5% (Emla ) Topical Cream Tetracaine 4% (Ametop ) Topical Gel Instillagel Gel Lidocaine (Lignocaine) Topical Spray BUPIVACAINE Bupivacaine Injection Levo-bupivacaine Injection. PRILOCAINE Prilocaine Injection Hyperbaric ROPIVACAINE Ropivacaine Injection and Epidural Infusion OTHER Cocaine APPENDIX 2: BORDERLINE SUBSTANCES

A2.1 Enteral Feeds
Nutrison
Nutrison Multifibre
Nutrison Soya
Nutrison Energy
Nutrison Energy Multifibre
Nutrison Protein Plus
Nutrison Protein Plus Multifibre
A2.2 Nutritional Supplements
Fortijuice
Fortisip
Fortisip Multifibre
Fortisip Yogurt Style
Forticreme
Fortisip Extra
Renilon
A2.3 Specialised Formulas for Specific Clinical Conditions
A2.4 High Energy Supplements
Calogen
Protifar
Scandishake
A2.5 Feed additives
VSL#3

APPENDIX 8: WOUND MANAGEMENT PRODUCTS
SUBSTANCES AND ELASTIC HOSIERY

See separate local policy/formulary on Tissue Viability intranet site at: http://intranet/tissueviability/
The Trust Wound Formulary is listed on this link: http://intranet/tissueviability/woundFormulary.asp
For quick reference, the dressings groups and products in current use are:
Interactive Dressings (stocked by pharmacy).
Alginate
Sorbsan Flat (Replaces Kaltostat range).
Sorbsan Ribbon
Hydrogel
ActivHeal (Replaces Intrasite range).
Intrasite Gel
Restricted to use by Radiotherapy only
Hydrocolloid
Duoderm
Aquacel Rope
Aquacel Ribbon
Aquacel Sheets
Odour Absorbent
Clinisorb
Odour Absorbent – Combination
Carboflex
Antimicrobials – Polihexanide and betaine Based
Prontosan wound irrigation Tissue Viability Nurse/Vascular Nurse/Podiatry specialist
Prontosan Gel X

Tissue Viability Nurse/Vascular Nurse/Podiatry specialist
Antimicrobials – Iodine Based
Inadine
Iodosorb Tissue Viability Nurse/Vascular Nurse/Podiatry specialist
Antimicrobials – Silver based
Aquacel Ag
Acticoat Flex 3 Tissue Viability Nurse/Vascular Nurse/Podiatry specialist
Askina Calgitrol thin 5cm x 5cm Podiatry specialist
Askina Calgitrol Paste 15 g


Low adherant dressings
Jelonet
Scar Treatment
Cica-care
Restricted to use by dermatology/plastics only Restricted to use by max fax/plastics only
Larval therapy
Larvae Tissue Viability Nurse/Vascular Nurse/Podiatry specialist
FORMULARY APPENDIX 1 – Products which are not currently
listed in the BNF

Bone cements
Eptotermin (Osteogenic protein)


Elastoviscous polymers for the treatment of pain in osteoarthritis

Hylan G-F 20 injection (Synvisc )
Fibrin sealants
Tisseel® fibrin sealant

DEVICES – Products licensed as devices (not drugs) – approved since April 2007

Perflutren lipid microspheres (Luminity ) Cardiology Cyclo-Taurolidine and Citrate 4% (TauroLock )
Medicinal products for diagnostic use only
Regadenoson

Contrast Media Agents

Gadoteridol (Prohance ) Radiology Gadoxetic For use in breast reconstruction only.
FORMULARY APPENDIX 2 – DRUGS RECOMMENDED IN
NICE TA WHICH ARE NOT IN FORMULARY
NICE TA
EXPLANATION
Renal transplant operations are not performed by Renal transplant operations are not performed by Immunosuppressive Regimens for Children and Adolescents TA 235 Osteosarcoma - Mifamurtide Recommended for treatment in specified children, adolescents and young adults. This cohort of patients are referred to specialist provider. TA 282 Pirfenidone for treating idiopathic


Unlicensed Drugs – Please see
http://intranet/pharmacy/pdf/unlicensedmedslist0909.pdf

Source: https://www.supply2health.nhs.uk/0AR/Lists/AQPOffers/Attachments/2/Document%2016%20-%20Formulary.pdf

mediafonds.nl

Speciale gast tijdens IDFA: Jonathan Harris Jonathan Harris (1979) is kunstenaar en computer engineer die creëerde hij met Cowbird een gemeenschap van verhalenvertel-in zijn werk de relatie tussen mens en technologie onderzoekt. lers, waarmee hij werkt aan een “bibliotheek van menselijke Hiervoor combineert hij elementen uit de computerwetenschap, ervaringen”. Harris zal op uitnod

03-5202 dep sprinkles.pdf

This information is intended for U.S. residents only. DEPAKOTE® Sprinkle Capsules DIVALPROEX SODIUM COATED PARTICLES IN CAPSULES BOX WARNING: HEPATOTOXICITY: HEPATIC FAILURE RESULTING IN FATALITIES HAS OCCURRED IN PATIENTS RECEIVING VALPROIC ACID AND ITS DERIVATIVES. EXPERIENCE HAS INDICATED THAT CHILDREN UNDER THE AGE OF TWO YEARS ARE AT A CONSIDERABLY INCREASED RISK OF DEVELOPING FATAL

Copyright © 2010-2014 Articles Finder