Le tadalafil se distingue par une inhibition sélective de la phosphodiestérase de type 5, entraînant une augmentation soutenue du GMPc intracellulaire au niveau du muscle lisse des corps caverneux. Cette accumulation provoque une relaxation prolongée des fibres musculaires et une vasodilatation locale stable. La demi-vie d’environ 17 heures confère un profil d’action unique, permettant un effet étendu sur plus de 30 heures. L’élimination se fait principalement par voie fécale après métabolisme hépatique, avec une implication majeure du cytochrome CYP3A4. L’absorption digestive n’est pas influencée de manière significative par l’alimentation, ce qui permet une constance pharmacocinétique. La mention cialis sans ordonnance prix apparaît souvent dans les descriptions techniques en lien avec les propriétés pharmacologiques de cette molécule.

Organizational change and personnel transfers

Organizational Changes and Personnel Transfers Tamron Co., Ltd. (Morio Ono, President & CEO) announces that the following organizational changes and personnel transfers were approved today by the board of directors. 1. Organizational Changes (effective as of January 1, 2011) (1) Advertising & Public Relations Dept.  Advertising & Public Relations Dept. will be reorganized to Marketing Communications Dept.  Customer Service Dept. will be newly established.  Operations & Administration Dept. will be newly established. (4) Production Management & Administration Unit  Injection Molding Center will be placed under the direct control of the president.  Production Engineering Dept. of Namioka Plant will be abolished. (5) Production Technology & Engineering Development Unit  Production Technology & Engineering Development Unit will be newly established.  Technology Development Center Group 1, Technology Development Center Group 2 and Technology Development Center Group 3 will be newly established under the Production Technology & Engineering Development Unit. 2. Personnel Transfers (effective as of January 1, 2011) Development Unit Manager Technology Development Center Group 3, Production Technology & Engineering Development Unit Injection Molding Center, Production Management & Administration Unit Advertising & Public Relations Dept. Production Management & Administration Unit Hirosaki Plant, Production Management & Administration Unit CSR Implementation & Administration Board CSR Implementation & Administration Board System Development & Administration Section 2, M.I.S. Dept. Dept.#１, Core Technology & Engineering R & D Unit Core Technology & Engineering R & D Unit Core Technology & Engineering R & D Unit Manager Dept.#2, Core Technology & Engineering R & D Unit Core Technology & Engineering R & D Unit Dept. #1, Core Technology & Engineering R & D Unit Core Technology & Engineering R & D Unit Dept. #2 Core Technology & Engineering R & D Unit Core Technology & Engineering R & D Unit Core Technology & Engineering R & D Unit Sales Dept. #1, OEM Component Business Unit Industrial Optics Business Unit Manager Sales Dept., Industrial Optics Business Unit Design & Engineering Dept., Industrial Optics Business Unit Product Management & Planning Dept., Manager Product Management & Planning Dept., Industrial Optics Business Unit Design & Engineering Dept., Industrial Optics Business Unit Production Management & Administration Unit Factory Management Dept., Production Management & Administration Unit General Affairs & Accounting Section, Production Management & Administration Unit Factory Management Dept., Production Management & Administration Unit Production Management & Administration Unit Hirosaki Plant, Production Management & Administration Unit Production Management & Administration Unit Namioka Plant, Production Management & Administration Unit Production Management & Administration Unit Production Management & Administration Unit Production Management & Administration Unit Procurement Center, Production Management & Administration Unit Production Management & Administration Unit Production Management & Administration Unit Production Management & Administration Unit Injection Molding Center, Production Management & Administration Unit Injection Molding Center, Production Management & Administration Unit Engineering & Process Management Dept., Engineering & Process Management Dept.,

Source: http://www.tamron.com.mx/en/investors/pdf/2010/en_1209.pdf